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High affinity nerve growth factor receptor

Summary

UniProt ID

Q3UFB7

Gene Symbol

Ntrk1

Organism

Mus musculus (house mouse)

External Links

PubChem: Q3UFB7

Annotation

Keyword

ATP-binding
Cell membrane
Developmental protein
Differentiation
Disulfide bond
Endosome
Glycoprotein
Immunoglobulin domain
Leucine-rich repeat
Neurogenesis
Phosphoprotein
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix
Tyrosine-protein kinase
Ubl conjugation

Gene Ontology (GO)

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GO Term
neuron development
programmed cell death involved in cell development
positive regulation of neuron projection development
olfactory nerve development
neuron projection development
response to nutrient levels
mechanoreceptor differentiation
positive regulation of programmed cell death
negative regulation of neuron apoptotic process
sympathetic nervous system development

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GO Term
cytoplasm
plasma membrane
axon
protein-containing complex
early endosome
late endosome
cell surface
recycling endosome
dendrite
neuronal cell body

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GO Term
ATP binding
kinase binding
protein homodimerization activity
GPI-linked ephrin receptor activity
neurotrophin receptor activity
neurotrophin p75 receptor binding
nerve growth factor receptor activity
neurotrophin binding
nerve growth factor binding
protein tyrosine kinase activity

Annotation information from UniProt.

Sequence

MLRGQRLGQLGWHRPAAGLGSLMTSLMLACASAASCREVCCPVGPSGLRCTRAGSLDTLRGLRGAGNLTELYVENQQHLQRLEFEDLQGLGELRSLTIVKSGLRFVAPDAFRFTPRLSHLNLSSNALESLSWKTVQGLSLQDLTLSGNPLHCSCALFWLQRWEQEGLCGVHTQTLHDSGPGDQFLPLGHNTSCGVPTVKIQMPNDSVEVGDDVFLQCQVEGLALQQADWILTELEGAATVKKFGDLPSLGLILVNVTSDLNKKNVTCWAENDVGRAEVSVQVSVSFPASVHLGLAVEQHHWCIPFSVDGQPAPSLRWLFNGSVLNETSFIFTQFLESALTNETMRHGCLRLNQPTHVNNGNYTLLAANPYGQAAASVMAAFMDNPFEFNPEDPIPVSFSPVDGNSTSRDPVEKKDETPFGVSVAVGLAVSAALFLSALLLVLNKCGQRSKFGINRPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIMENPQYFSDTCVHHIKRQDIILKWELGEGAFGKVFLAECYNLLNDQDKMLVAVKALKEASENARQDFQREAELLTMLQHQHIVRFFGVCTEGGPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLASLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFSTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIECITQGRELERPRACPPDVYAIMRGCWQREPQQRLSMKDVHARLQALAQAPPSYLDVLG

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

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Position	Description	Source
67	N-linked (GlcNAc...) asparagine	UniProt
121	N-linked (GlcNAc...) asparagine	UniProt
190	N-linked (GlcNAc...) asparagine	UniProt
204	N-linked (GlcNAc...) asparagine	UniProt
255	N-linked (GlcNAc...) asparagine	UniProt
264	N-linked (GlcNAc...) asparagine	UniProt
320	N-linked (GlcNAc...) asparagine	UniProt
325	N-linked (GlcNAc...) asparagine	UniProt
341	N-linked (GlcNAc...) asparagine	UniProt
361	N-linked (GlcNAc...) asparagine	UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 5** entries
Pathway Name	Organism
ARMS-mediated activation	Mus musculus
Frs2-mediated activation	Mus musculus
PI3K/AKT activation	Mus musculus
Retrograde neurotrophin signalling	Mus musculus
TRKA activation by NGF	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

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Annotation

International Collaboration

Acknowledgements