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MIRAGE
Histone-lysine N-methyltransferase KMT5B

Summary
UniProt ID
Q4FZB7
Gene Symbol
  • CGI-85
  • KMT5B
  • SUV420H1
Gene ID
51111
Organism
Homo sapiens (human)
GlyConnect
GlyGen
Q4FZB7
PubChem
Q4FZB7
The Human Metabolome Database
HMDBP09038
The O-GlcNAc Database
Q4FZB7
O-GlcNAcAtlas
Q4FZB7
Re-Glyco
Q4FZB7
Annotation
Keyword
  • 3D-structure
  • Alternative splicing
  • Chromatin regulator
  • Chromosome
  • Disease variant
  • Intellectual disability
  • Isopeptide bond
  • Metal-binding
  • Methyltransferase
  • Myogenesis
  • Nucleus
  • Reference proteome
  • Repressor
  • S-adenosyl-L-methionine
  • Transcription regulation
  • Ubl conjugation
  • Zinc
Gene Ontology (GO)
Displaying all 3 entries
GO Term
nucleus
nucleoplasm
condensed chromosome, centromeric region
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Annotation information from UniProt.
Sequence
MKWLGESKNMVVNGRRNGGKLSNDHQQNQSKLQHTGKDTLKAGKNAVERRSNRCNGNSGFEGQSRYVPSSGMSAKELCENDDLATSLVLDPYLGFQTHKMNTSAFPSRSSRHFSKSDSFSHNNPVRFRPIKGRQEELKEVIERFKKDEHLEKAFKCLTSGEWARHYFLNKNKMQEKLFKEHVFIYLRMFATDSGFEILPCNRYSSEQNGAKIVATKEWKRNDKIELLVGCIAELSEIEENMLLRHGENDFSVMYSTRKNCAQLWLGPAAFINHDCRPNCKFVSTGRDTACVKALRDIEPGEEISCYYGDGFFGENNEFCECYTCERRGTGAFKSRVGLPAPAPVINSKYGLRETDKRLNRLKKLGDSSKNSDSQSVSSNTDADTTQEKNNATSNRKSSVGVKKNSKSRTLTRQSMSRIPASSNSTSSKLTHINNSRVPKKLKKPAKPLLSKIKLRNHCKRLEQKNASRKLEMGNLVLKEPKVVLYKNLPIKKDKEPEGPAQAAVASGCLTRHAAREHRQNPVRGAHSQGESSPCTYITRRSVRTRTNLKEASDIKLEPNTLNGYKSSVTEPCPDSGEQLQPAPVLQEEELAHETAQKGEAKCHKSDTGMSKKKSRQGKLVKQFAKIEESTPVHDSPGKDDAVPDLMGPHSDQGEHSGTVGVPVSYTDCAPSPVGCSVVTSDSFKTKDSFRTAKSKKKRRITRYDAQLILENNSGIPKLTLRRRHDSSSKTNDQENDGMNSSKISIKLSKDHDNDNNLYVAKLNNGFNSGSGSSSTKLKIQLKRDEENRGSYTEGLHENGVCCSDPLSLLESRMEVDDYSQYEEESTDDSSSSEGDEEEDDYDDDFEDDFIPLPPAKRLRLIVGKDSIDIDISSRRREDQSLRLNA
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying all 2 entries
Position Description PubMed ID GlyTouCan ID Source
407
711
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying 1 entry
Pathway Name Organism
PKMTs methylate histone lysines Homo sapiens
Disease
Displaying 1 entry
DO ID Disease Name Source
DOID:0080232 autosomal dominant intellectual developmental disorder 51
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 8, 2025