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Clusterin

Summary

UniProt ID

Q549A5

Gene Symbol

Clu

Gene ID

12759

Organism

Mus musculus (house mouse)

External Links

GlycoProtDB: GPDB0005245
Re-Glyco: Q549A5

Annotation

Keyword

Chaperone
Coiled coil
Cytoplasm
Cytoplasmic vesicle
Disulfide bond
Endoplasmic reticulum
Glycoprotein
Membrane
Mitochondrion
Nucleus
Secreted
Signal
Ubl conjugation

Gene Ontology (GO)

Displaying entries **1 - 10** of 11 in total

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GO Term
cell periphery
cytosol
cell surface
chromaffin granule
apical dendrite
neurofibrillary tangle
perinuclear endoplasmic reticulum lumen
spherical high-density lipoprotein particle
nucleus
mitochondrial inner membrane

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying entries **1 - 10** of 27 in total

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GO Term
response to virus
central nervous system myelin maintenance
regulation of cell population proliferation
positive regulation of NF-kappaB transcription factor activity
protein stabilization
regulation of amyloid-beta clearance
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
positive regulation of neurofibrillary tangle assembly
negative regulation of response to endoplasmic reticulum stress
cell morphogenesis

Displaying **all 9** entries
GO Term
unfolded protein binding
protein carrier chaperone
amyloid-beta binding
ubiquitin protein ligase binding
protein-containing complex binding
low-density lipoprotein particle receptor binding
misfolded protein binding
receptor ligand activity
tau protein binding

Annotation information from UniProt.

Sequence

MKILLLCVALLLIWDNGMVLGEQEVSDNELQELSTQGSRYINKEIQNAVQGVKHIKTLIEKTNAERKSLLNSLEEAKKKKEDALEDTRDSEMKLKAFPEVCNETMMALWEECKPCLKHTCMKFYARVCRSGSGLVGQQLEEFLNQSSPFYFWMNGDRIDSLLESDRQQSQVLDAMQDSFARASGIIDTLFQDRFFARELHDPHYFSPIGFPHKRPHFLYPKSRLVRSLMSPSHYGPPSFHNMFQPFFEMIHQAQQAMDVQLHSPAFQFPDVDFLREGEDDRTVCKEIRRNSTGCLKMKGQCEKCQEILSVDCSTNNPAQANLRQELNDSLQVAERLTEQYKELLQSFQSKMLNTSSLLEQLNDQFNWVSQLANLTQGEDKYYLRVSTVTTHSSDSEVPSRVTEVVVKLFDSDPITVVLPEEVSKDNPKFMDTVAEKALQEYRRKSRAE

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites