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E3 ubiquitin-protein ligase BRE1A

Summary

UniProt ID

Q5DTM8

Gene Symbol

Bre1a
Kiaa4116
Rnf20

Gene ID

109331

Organism

Mus musculus (house mouse)

External Links

GlyGen: Q5DTM8
PubChem: Q5DTM8
O-GlcNAcAtlas: Q5DTM8
Re-Glyco: Q5DTM8

Annotation

Keyword

Acetylation
Alternative splicing
Chromatin regulator
Coiled coil
Nucleus
Phosphoprotein
Reference proteome
Transferase
Ubl conjugation pathway
Zinc-finger

Gene Ontology (GO)

Displaying **all 3** entries
GO Term
nucleoplasm
HULC complex
nucleolus

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying **all 4** entries
GO Term
negative regulation of cell migration
positive regulation of transcription by RNA polymerase II
protein polyubiquitination
ubiquitin-dependent protein catabolic process

Displaying **all 9** entries
GO Term
chromatin binding
transcription coactivator activity
metal ion binding
p53 binding
mRNA 3'-UTR binding
ubiquitin protein ligase binding
histone binding
identical protein binding
histone H2B C-terminal K residue ubiquitin ligase activity

Annotation information from UniProt.

Sequence

MSGIGNKRAAGEPGTSMPPEKKTAVEDSGTTVETIKLGGVSSTEELDIRTLQSKNRKLAEMLDQRQAIEDELREHIEKLERRQATDDASLLIVNRYWSQFDENIRIILKRYDLDQGLGDLLTERKALVVPEPEPDSDSNQERKDDRERGDGQEPAFSFLATLASSSSEEMESQLQERVESSRRAVSQIVTVYDKLQEKVDLLSRKLNSGDNLIVEEAVQELNSFLAQENVRLQELTDLLQEKHHTMSQEFCKLQGKVETAESRVSVLESMIDDLQWDIDKIRKREQRLNRHLAEVLERVNSKGYKVYGAGSSLYGGTITINARKFEEMNAELEENKELAQNRHCELEKLRQDFEEVTTQNEKLKVELRSAVEEVVKETPEYRCMQSQFSVLYNESLQLKAHLDEARTLLHGTRGTHQRQVELIERDEVSLHKKLRTEVIQLEDTLAQVRKEYEMLRIEFEQTLAANEQAGPINREMRHLISSLQNHNHQLKGEVLRYKRKLREAQSDLNKTRLRSGSALLQSQSSTEDPKDEPTELKQDSEDLATHSSALKASQEDEVKSKRDEEERERERREKEREREREREKEKEREREKQKLKESEKERDSVKDKEKGKHDDGRKKEAEIIKQLKIELKKAQESQKEMKLLLDMYRSAPKEQRDKVQLMAAEKKSKAELEDLRQRLKDLEDKEKKENKKMADEDALRKIRAVEEQIEYLQKKLAMAKQEEEALLSEMDVTGQAFEDMQEQNIRLMQQLREKDDANFKLMSERIKSNQIHKLLKEEKEELADQVLTLKTQVDAQLQVVRKLEEKEHLLQSNIGTGEKELGLRTQALEMNKRKAMEAAQLADDLKAQLELAQKKLHDFQDEIVENSVTKEKDLFNFKRAQEDISRLRRKLETTKKPDNVPKCDEILMEEIKDYKARLTCPCCNMRKKDAVLTKCFHVFCFECVKTRYDTRQRKCPKCNAAFGANDFHRIYIG

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites