Arylsulfatase I

Summary
UniProt ID
Q5FYB1
Gene Symbol
  • ARSI
Organism
Homo sapiens (human)
External Links
The Human Metabolome Database
HMDBP07459
RaftProt
Q5FYB1
Annotation
Keyword
  • Alternative splicing
  • Calcium
  • Endoplasmic reticulum
  • Glycoprotein
  • Hydrolase
  • Metal-binding
  • Oxidation
  • Reference proteome
  • Secreted
  • Signal
Gene Ontology (GO)
Displaying all 2 entries
GO Term
extracellular region
endoplasmic reticulum lumen
Displaying all 2 entries
GO Term
metal ion binding
arylsulfatase activity
Sequence
MHTLTGFSLVSLLSFGYLSWDWAKPSFVADGPGEAGEQPSAAPPQPPHIIFILTDDQGYHDVGYHGSDIETPTLDRLAAKGVKLENYYIQPICTPSRSQLLTGRYQIHTGLQHSIIRPQQPNCLPLDQVTLPQKLQEAGYSTHMVGKWHLGFYRKECLPTRRGFDTFLGSLTGNVDYYTYDNCDGPGVCGFDLHEGENVAWGLSGQYSTMLYAQRASHILASHSPQRPLFLYVAFQAVHTPLQSPREYLYRYRTMGNVARRKYAAMVTCMDEAVRNITWALKRYGFYNNSVIIFSSDNGGQTFSGGSNWPLRGRKGTYWEGGVRGLGFVHSPLLKRKQRTSRALMHITDWYPTLVGLAGGTTSAADGLDGYDVWPAISEGRASPRTEILHNIDPLYNHAQHGSLEGGFGIWNTAVQAAIRVGEWKLLTGDPGYGDWIPPQTLATFPGSWWNLERMASVRQAVWLFNISADPYEREDLAGQRPDVVRTLLARLAEYNRTAIPVRYPAENPRAHPDFNGGAWGPWASDEEEEEEEGRARSFSRGRRKKKCKICKLRSFFRKLNTRLMSQRI
Glycosylation Sites
Displaying all 4 entries
Position Description PubMed ID GlyTouCan ID Source
276 N-linked (GlcNAc...) asparagine
288 N-linked (GlcNAc...) asparagine
466 N-linked (GlcNAc...) asparagine
496 N-linked (GlcNAc...) asparagine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 2 entries
Pathway Name Organism
Glycosphingolipid catabolism Homo sapiens
The activation of arylsulfatases Homo sapiens
Disease
Displaying entries 1 - 10 of 34 in total
DO ID Disease Name Source
DOID:0050572 cone-rod dystrophy
DOID:10534 stomach cancer
DOID:10584 retinitis pigmentosa
DOID:1059 intellectual disability
DOID:11105 fundus albipunctatus
DOID:114 heart disease
DOID:11836 clubfoot
DOID:12139 dysthymic disorder
DOID:12849 autistic disorder
DOID:1287 cardiovascular system disease

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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 19, 2024