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Toll-like receptor 9

Summary

UniProt ID

Q5I2M5

Gene Symbol

TLR9

Organism

Bos taurus (cattle)

External Links

PubChem: Q5I2M5

Annotation

Keyword

3D-structure
Cytoplasmic vesicle
Disulfide bond
Endoplasmic reticulum
Endosome
Glycoprotein
Inflammatory response
Innate immunity
Leucine-rich repeat
Lysosome
Palmitate
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 10** of 17 in total

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GO Term
canonical NF-kappaB signal transduction
positive regulation of NF-kappaB transcription factor activity
activation of innate immune response
toll-like receptor signaling pathway
positive regulation of MAPK cascade
defense response to virus
positive regulation of interferon-alpha production
positive regulation of interferon-beta production
positive regulation of toll-like receptor 9 signaling pathway
positive regulation of immunoglobulin production

Displaying **all 7** entries
GO Term
lysosome
plasma membrane
early phagosome
endosome
endoplasmic reticulum
endoplasmic reticulum membrane
endolysosome

Displaying **all 4** entries
GO Term
pattern recognition receptor activity
protein homodimerization activity
unmethylated CpG binding
siRNA binding

Annotation information from UniProt.

Sequence

MGPYCAPHPLSLLVQAAALAAALAEGTLPAFLPCELQPHGQVDCNWLFLKSVPHFSAGAPRANVTSLSLISNRIHHLHDSDFVHLSNLRVLNLKWNCPPAGLSPMHFPCRMTIEPNTFLAVPTLEELNLSYNGITTVPALPSSLVSLSLSHTSILVLGPTHFTGLHALRFLYMDGNCYYMNPCPRALEVAPGALLGLGNLTHLSLKYNNLTEVPRRLPPSLDTLLLSYNHIVTLAPEDLANLTALRVLDVGGNCRRCDHARNPCRECPKNFPKLHPDTFSHLSRLEGLVLKDSSLYKLEKDWFRGLGRLQVLDLSENFLYDYITKTTIFNDLTQLRRLNLSFNYHKKVSFAHLHLASSFGSLVSLEKLDMHGIFFRSLTNITLQSLTRLPKLQSLHLQLNFINQAQLSIFGAFPSLLFVDLSDNRISGAATPAAALGEVDSRVEVWRLPRGLAPGPLDAVSSKDFMPSCNLNFTLDLSRNNLVTIQQEMFTRLSRLQCLRLSHNSISQAVNGSQFVPLTSLRVLDLSHNKLDLYHGRSFTELPQLEALDLSYNSQPFSMQGVGHNLSFVAQLPSLRYLSLAHNGIHSRVSQKLSSASLRALDFSGNSLSQMWAEGDLYLCFFKGLRNLVQLDLSENHLHTLLPRHLDNLPKSLRQLRLRDNNLAFFNWSSLTVLPRLEALDLAGNQLKALSNGSLPPGIRLQKLDVSSNSIGFVIPGFFVRATRLIELNLSANALKTVDPSWFGSLAGTLKILDVSANPLHCACGAAFVDFLLERQEAVPGLSRRVTCGSPGQLQGRSIFTQDLRLCLDETLSLDCFGLSLLMVALGLAVPMLHHLCGWDLWYCFHLCLAHLPRRRRQRGEDTLLYDAVVVFDKVQSAVADWVYNELRVQLEERRGRRALRLCLEERDWLPGKTLFENLWASVYSSRKTMFVLDHTDRVSGLLRASFLLAQQRLLEDRKDVVVLVILRPAAYRSRYVRLRQRLCRQSVLLWPHQPSGQGSFWANLGIALTRDNRHFYNRNFCRGPTTAE

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying entries **1 - 10** of 13 in total

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Position	Description	Source
63	N-linked (GlcNAc...) asparagine	UniProt
128	N-linked (GlcNAc...) asparagine	UniProt
199	N-linked (GlcNAc...) asparagine	UniProt
209	N-linked (GlcNAc...) asparagine	UniProt
241	N-linked (GlcNAc...) asparagine	UniProt
339	N-linked (GlcNAc...) asparagine	UniProt
380	N-linked (GlcNAc...) asparagine	UniProt
472	N-linked (GlcNAc...) asparagine	UniProt
511	N-linked (GlcNAc...) asparagine	UniProt
565	N-linked (GlcNAc...) asparagine	UniProt