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Complement factor I

Summary

UniProt ID

Q5R5A4

Gene Symbol

CFI

Gene ID

100189676

Organism

Pongo abelii (Sumatran orangutan)

External Links

PubChem: Q5R5A4
Re-Glyco: Q5R5A4

Annotation

Keyword

Calcium
Cleavage on pair of basic residues
Complement pathway
Disulfide bond
Glycoprotein
Metal-binding
Reference proteome
Repeat
Secreted
Serine protease
Signal

Gene Ontology (GO)

Displaying **all 2** entries
GO Term
extracellular region
membrane

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying **all 3** entries
GO Term
proteolysis
innate immune response
complement activation, classical pathway

Displaying **all 2** entries
GO Term
serine-type endopeptidase activity
metal ion binding

Annotation information from UniProt.

Sequence

MKLLHVFLLFLCFHLSFCKVTYTSQEDLVEKKCLAKKHTHLSCNKVFCQPWQICIEGTCICKLPYQCPKNGTTVCATNGRSFPTYCQQKSLECLRPGTKFLNNGTCTAEGKFSVSLKHGNTDSEGIVEVKLVDQDKTMFICKSSWSMREANVACLDLGFQQGADTQRRFKLSNLSINSTECLHVHCRGLETSLAECTFTKRRTMGYQDLADVVCYTQKADSPTNDFFQCVNGKYISQMKACDGINDCGDQSDELCCKACQGKSFHCKSGVCIPSQYRCNGEVDCITGEDEVGCEGFASVAQEETEILTADMDAERRRIKSLLPKLSCGVKNRRHIRRKRIVGGKRAQLGDLPWQVGIKDASGITCGGIYIGGCWILTAAHCLRASKTHHYQIWTTVVDWIHPDRKRIVIEYVDRIIFHENYNAGTYQNDIALMEMKKDGNKKDCELPRSIPACVPWSPYLFQPNDTCIVSGWGREKDNEKVFSLQWGEVKLISNCSKFYGNRFYEKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWISYHVGRPFISQYNV

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 7** entries
Position	Description	Source
70	N-linked (GlcNAc...) asparagine	UniProt
103	N-linked (GlcNAc...) asparagine	UniProt
173	N-linked (GlcNAc...) asparagine	UniProt
177	N-linked (GlcNAc...) asparagine	UniProt
464	N-linked (GlcNAc...) asparagine	UniProt
494	N-linked (GlcNAc...) asparagine	UniProt
536	N-linked (GlcNAc...) asparagine	UniProt