GlyCosmos Portal

Submissions

Neprilysin

Summary

UniProt ID

Q5RE69

Gene Symbol

MME

Gene ID

100173750

Organism

Pongo abelii (Sumatran orangutan)

External Links

PubChem: Q5RE69
Re-Glyco: Q5RE69

Annotation

Keyword

Cell membrane
Disulfide bond
Glycoprotein
Metal-binding
Metalloprotease
Myristate
Phosphoprotein
Reference proteome
Signal-anchor
Transmembrane helix
Zinc

Gene Ontology (GO)

Displaying entries **1 - 10** of 12 in total

1

2

Next ›

Last »
GO Term
cytoplasm
plasma membrane
axon
dendrite
neuronal cell body
synapse
early endosome
trans-Golgi network
brush border
synaptic vesicle

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying entries **1 - 10** of 18 in total

1

2

Next ›

Last »
GO Term
neuropeptide processing
cellular response to UV-A
positive regulation of long-term synaptic potentiation
positive regulation of neurogenesis
cellular response to cytokine stimulus
creatinine metabolic process
replicative senescence
kidney development
substance P catabolic process
bradykinin catabolic process

Displaying **all 7** entries
GO Term
zinc ion binding
exopeptidase activity
metalloendopeptidase activity
peptide binding
protein homodimerization activity
phosphatidylserine binding
cardiolipin binding

Annotation information from UniProt.

Sequence

MGKSESQMDITDINTPKPKKKQRWTPLEISLSVLVLLLTIIAVTMIALYATYDDGICKSSDCIKSAARLIQNMDATAEPCTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELEVVLKDVLQEPKTEDIVAVQKAKTLYRSCINESAIDSRGGEPLLKLLPDVYGWPVATENWEQKYGASWTAEKAIAQLNSKYGKKVLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYECTGIYKEACTAYVDFMISVARLIRQEERLPIDENQLALEMNKVMELEKEIANATAKPEDRNDPMLLYKKMTLAQIQNNFSLEINGKPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLTKLKPILTKYSARDLQNLMSWRFIMDLVSSLSRTYKESRNAFRKALYGTTSETATWRRCANYVNGNMENAVGRLYVEAAFAGESKHVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKALAIKERIGYPDDIVSNDNKLNNEYLELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDEWISGAAVVNAFYSSGRNQIVFPAGILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKDGDLVDWWTQQSASNFKEQSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGLGQAYRAYQNYIKKNGEEKLLPGLDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRIIGTLQNSAEFSEAFHCRKNSYMNPEKKCRVW

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 6** entries
Position	Description	Source
145	N-linked (GlcNAc...) asparagine	UniProt
285	N-linked (GlcNAc...) asparagine	UniProt
311	N-linked (GlcNAc...) asparagine	UniProt
325	N-linked (GlcNAc...) asparagine	UniProt
335	N-linked (GlcNAc...) asparagine	UniProt
628	N-linked (GlcNAc...) asparagine	UniProt