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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Glycoprotein endo-alpha-1,2-mannosidase
Summary
- UniProt ID
- Q5SRI9
- Gene Symbol
-
- MANEA
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Golgi apparatus
- Hydrolase
- Reference proteome
- Signal-anchor
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| Golgi membrane |
| Golgi apparatus |
| GO Term |
|---|
| alpha-mannosidase activity |
| glycoprotein endo-alpha-1,2-mannosidase activity |
Sequence
MAKFRRRTCIILALFILFIFSLMMGLKMLRPNTATFGAPFGLDLLPELHQRTIHLGKNFDFQKSDRINSETNTKNLKSVEITMKPSKASELNLDELPPLNNYLHVFYYSWYGNPQFDGKYIHWNHPVLEHWDPRIAKNYPQGRHNPPDDIGSSFYPELGSYSSRDPSVIETHMRQMRSASIGVLALSWYPPDVNDENGEPTDNLVPTILDKAHKYNLKVTFHIEPYSNRDDQNMYKNVKYIIDKYGNHPAFYRYKTKTGNALPMFYVYDSYITKPEKWANLLTTSGSRSIRNSPYDGLFIALLVEEKHKYDILQSGFDGIYTYFATNGFTYGSSHQNWASLKLFCDKYNLIFIPSVGPGYIDTSIRPWNTQNTRNRINGKYYEIGLSAALQTRPSLISITSFNEWHEGTQIEKAVPKRTSNTVYLDYRPHKPGLYLELTRKWSEKYSKERATYALDRQLPVS
Glycosylation Sites
G57321FI
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| N-glycan trimming and elongation in the cis-Golgi | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060000 | infective endocarditis | |
| DOID:10314 | endocarditis | |
| DOID:11257 | social phobia | |
| DOID:11612 | polycystic ovary syndrome | |
| DOID:1229 | paranoid schizophrenia | |
| DOID:150 | disease of mental health | |
| DOID:1612 | breast cancer | |
| DOID:162 | cancer | |
| DOID:2030 | anxiety disorder | |
| DOID:2468 | psychotic disorder |
