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Paired amphipathic helix protein Sin3a

Summary

UniProt ID

Q60520

Gene Symbol

Sin3a
Kiaa4126

Organism

Mus musculus (house mouse)

External Links

GlyGen: Q60520
PubChem: Q60520
The O-GlcNAc Database: Q60520
O-GlcNAcAtlas: Q60520

Annotation

Keyword

3D-structure
Acetylation
Alternative splicing
Biological rhythms
Coiled coil
Isopeptide bond
Nucleus
Phosphoprotein
Reference proteome
Repeat
Repressor
Transcription regulation
Ubl conjugation

Gene Ontology (GO)

Displaying entries **1 - 10** of 29 in total

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GO Term
regulation of DNA-templated transcription
negative regulation of circadian rhythm
negative regulation of DNA-templated transcription
activation of innate immune response
positive regulation of defense response to virus by host
DNA replication
type I interferon-mediated signaling pathway
positive regulation of G2/M transition of mitotic cell cycle
heterochromatin formation
cellular response to tert-butyl hydroperoxide

Displaying **all 10** entries
GO Term
chromatin
nucleus
nucleolus
protein-containing complex
transcription repressor complex
Sin3-type complex
histone deacetylase complex
kinetochore
nucleoplasm
transcription regulator complex

Displaying **all 7** entries
GO Term
DNA binding
chromatin binding
RNA binding
protein-containing complex binding
RNA polymerase II-specific DNA-binding transcription factor binding
transcription regulator inhibitor activity
transcription corepressor activity

Annotation information from UniProt.

Sequence

MKRRLDDQESPVYAAQQRRIPGSTEAFSHQHRVLAPAPPVYEAVSETMQSATGIQYSVAPNYQVSAVPQSSGSHGPAIAAVHSSHHHPTAVQPHGGQVVQSHAHPAPPVAPVQGQQQFQRLKVEDALSYLDQVKLQFGSQPQVYNDFLDIMKEFKSQSIDTPGVISRVSQLFKGHPDLIMGFNTFLPPGYKIEVQTNDMVNVTTPGQVHQIPTHGIQPQPQPPPQHPSQPSSQSAPTPAQPAPQPTAAKVSKPSQLQAHTPASQQTPPLPPYASPRSPPVQPHTPVTISLGTAPSLQNNQPVEFNHAINYVNKIKNRFQGQPDIYKAFLEILHTYQKEQRNAKEAGGNYTPALTEQEVYAQVARLFKNQEDLLSEFGQFLPDANSSVLLSKTTAEKVDSVRNDHGGTVKKPQLNNKPQRPSQNGCQIRRHSGTGATPPVKKKPKLMSLKESSMADASKHGVGTESLFFDKVRKALRSAEAYENFLRCLVIFNQEVISRAELVQLVSPFLGKFPELFNWFKNFLGYKESVHLESFPKERATEGIAMEIDYASCKRLGSSYRALPKSYQQPKCTGRTPLCKEVLNDTWVSFPSWSEDSTFVSSKKTQYEEHIYRCEDERFELDVVLETNLATIRVLEAIQKKLSRLSAEEQAKFRLDNTLGGTSEVIHRKALQRIYADKAADIIDGLRKNPSIAVPIVLKRLKMKEEEWREAQRGFNKVWREQNEKYYLKSLDHQGINFKQNDTKVLRSKSLLNEIESIYDERQEQATEENAGVPVGPHLSLAYEDKQILEDAAALIIHHVKRQTGIQKEDKYKIKQIMHHFIPDLLFAQRGDLSDVEEEEEEEMDVDEATGAPKKHNGVGGSPPKSKLLFSNTAAQKLRGMDEVYNLFYVNNNWYIFMRLHQILCLRLLRICSQAERQIEEENREREWEREVLGIKRDKSDSPAIQLRLKEPMDVDVEDYYPAFLDMVRSLLDGNIDSSQYEDSLREMFTIHAYIAFTMDKLIQSIVRQLQHIVSDEVCVQVTDLYLAENNNGATGGQLNSQTSRSLLESAYQRKAEQLMSDENCFKLMFIQSQGQVQLTVELLDTEEENSDDPVEAERWSDYVERYMSSDTTSPELREHLAQKPVFLPRNLRRIRKCQRGREQQEKEGKEGNSKKTMENVESLDKLECRFKLNSYKMVYVIKSEDYMYRRTALLRAHQSHERVSKRLHQRFQAWVDKWTKEHVPREMAAETSKWLMGEGLEGLVPCTTTCDTETLHFVSINKYRVKYGTVFKAP

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 4** entries
Position	GlyTouCan ID	Source
28	G49108TO	GlyGen The O-GlcNAc Database
251	G49108TO	GlyGen The O-GlcNAc Database
266	G49108TO	GlyGen The O-GlcNAc Database
295	G49108TO	GlyGen The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 6** entries
Pathway Name	Organism
Cytoprotection by HMOX1	Mus musculus
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function	Mus musculus
Regulation of MECP2 expression and activity	Mus musculus
Regulation of MITF-M-dependent genes involved in apoptosis	Mus musculus
Regulation of lipid metabolism by PPARalpha	Mus musculus
SUMOylation of transcription cofactors	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

Tools

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Summary

External Links

Annotation

International Collaboration

Acknowledgements