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Oxysterols receptor LXR-beta

Summary

UniProt ID

Q60644

Gene Symbol

Nr1h2
Lxrb
Rip15
Unr
Unr2

Organism

Mus musculus (house mouse)

External Links

GlyGen: Q60644
PubChem: Q60644
The O-GlcNAc Database: Q60644

Annotation

Keyword

Activator
DNA-binding
Isopeptide bond
Nucleus
Receptor
Reference proteome
Transcription regulation
Ubl conjugation
Zinc-finger

Gene Ontology (GO)

Displaying entries **1 - 10** of 29 in total

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GO Term
positive regulation of gene expression
negative regulation of gene expression
cell differentiation
cellular lipid metabolic process
hormone-mediated signaling pathway
negative regulation of lipid transport
positive regulation of fatty acid biosynthetic process
negative regulation of proteolysis
positive regulation of protein metabolic process
lipid homeostasis

Displaying **all 3** entries
GO Term
nucleus
cytoplasm
RNA polymerase II transcription regulator complex

Displaying entries **1 - 10** of 11 in total

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GO Term
DNA binding
ATPase binding
chromatin DNA binding
nuclear retinoid X receptor binding
DNA-binding transcription factor activity, RNA polymerase II-specific
DNA-binding transcription activator activity, RNA polymerase II-specific
DNA-binding transcription factor activity
nuclear receptor activity
RNA polymerase II cis-regulatory region sequence-specific DNA binding
zinc ion binding

Annotation information from UniProt.

Sequence

MSSPTSSLDTPVPGNGSPQPSTSATSPTIKEEGQETDPPPGSEGSSSAYIVVILEPEDEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVHGGAGRYACRGSGTCQMDAFMRRKCQLCRLRKCKEAGMREQCVLSEEQIRKKRIQKQQQQQPPPPSEPAASSSGRPAASPGTSEASSQGSGEGEGIQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPSRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
			G49108TO	GlyGen The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 5** entries
Pathway Name	Organism
LXRs regulate gene expression linked to cholesterol transport and efflux	Mus musculus
LXRs regulate gene expression to control bile acid homeostasis	Mus musculus
Nuclear Receptor transcription pathway	Mus musculus
SUMOylation of intracellular receptors	Mus musculus
VLDLR internalisation and degradation	Mus musculus