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Growth factor receptor-bound protein 10

Summary

UniProt ID

Q60760

Gene Symbol

Grb10
Meg1

Gene ID

14783

Organism

Mus musculus (house mouse)

External Links

GlyGen: Q60760
PubChem: Q60760
Re-Glyco: Q60760

Annotation

Keyword

3D-structure
Alternative splicing
Cytoplasm
Phosphoprotein
Reference proteome
SH2 domain

Gene Ontology (GO)

Displaying **all 2** entries
GO Term
protein-containing complex
cytosol

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying entries **1 - 10** of 12 in total

1

2

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GO Term
gene expression
signal transduction
negative regulation of phosphorylation
negative regulation of glycogen biosynthetic process
negative regulation of glucose import
vascular associated smooth muscle cell migration
negative regulation of Wnt signaling pathway
negative regulation of insulin receptor signaling pathway
insulin-like growth factor receptor signaling pathway
ERK1 and ERK2 cascade

Displaying **all 4** entries
GO Term
phosphotyrosine residue binding
insulin receptor binding
protein-macromolecule adaptor activity
signaling receptor complex adaptor activity

Annotation information from UniProt.

Sequence

MNNDINSSVESLNSACNMQSDTDTAPLLEDGQHASNQGAASSSRGQPQASPRQKMQRSQPVHILRRLQEEDQQLRTASLPAIPNPFPELTGAAPGSPPSVAPSSLPPPPSQPPAKHCGRCEKWIPGENTRGNGKRKIWRWQFPPGFQLSKLTRPGLWTKTTARFSKKQPKNQCPTDTVNPVARMPTSQMEKLRLRKDVKVFSEDGTSKVVEILTDMTARDLCQLLVYKSHCVDDNSWTLVEHHPQLGLERCLEDHEIVVQVESTMPSESKFLFRKNYAKYEFFKNPVNFFPDQMVNWCQQSNGGQAQLLQNFLNTSSCPEIQGFLQVKEVGRKSWKKLYVCLRRSGLYYSTKGTSKEPRHLQLLADLEESSIFYLIAGKKQYNAPNEHGMCIKPNKAKTEMKELRLLCAEDEQIRTCWMTAFRLLKYGMLLYQNYRIPQRKGLPPPFNAPMRSVSENSLVAMDFSGQIGRVIDNPAEAQSAALEEGHAWRKRSTRMNILSSQSPLHPSTLNAVIHRTQHWFHGRISREESHRIIKQQGLVDGLFLLRDSQSNPKAFVLTLCHHQKIKNFQILPCEDDGQTFFTLDDGNTKFSDLIQLVDFYQLNKGVLPCKLKHHCIRVAL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
6			G02815KT	GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 6** entries
Pathway Name	Organism
FLT3 Signaling	Mus musculus
IRS activation	Mus musculus
Insulin receptor signalling cascade	Mus musculus
RET signaling	Mus musculus
Signal attenuation	Mus musculus
Signaling by SCF-KIT	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

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Summary

External Links

Annotation

International Collaboration

Acknowledgements