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Receptor-interacting serine/threonine-protein kinase 1

Summary

UniProt ID

Q60855

Gene Symbol

Ripk1
Rinp
Rip

Organism

Mus musculus (house mouse)

External Links

GlyGen: Q60855
PubChem: Q60855
The O-GlcNAc Database: Q60855

Annotation

Keyword

3D-structure
ATP-binding
Apoptosis
Cell membrane
Cytoplasm
Host-virus interaction
Inflammatory response
Isopeptide bond
Necrosis
Phosphoprotein
Reference proteome
Serine/threonine-protein kinase
Ubl conjugation

Gene Ontology (GO)

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GO Term
positive regulation of neuron apoptotic process
positive regulation of macrophage differentiation
T cell apoptotic process
positive regulation of execution phase of apoptosis
regulation of reactive oxygen species metabolic process
positive regulation of necroptotic process
negative regulation of necroptotic process
necroptotic process
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
protein autophosphorylation

Displaying **all 5** entries
GO Term
receptor complex
death-inducing signaling complex
mitochondrion
ripoptosome
protein-containing complex

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GO Term
protein kinase activity
protein serine/threonine kinase activity
protein-containing complex binding
death domain binding
ubiquitin protein ligase binding
protein homodimerization activity
JUN kinase kinase kinase activity
death receptor binding
ATP binding
signaling adaptor activity

Annotation information from UniProt.

Sequence

MQPDMSLDNIKMASSDLLEKTDLDSGGFGKVSLCYHRSHGFVILKKVYTGPNRAEYNEVLLEEGKMMHRLRHSRVVKLLGIIIEEGNYSLVMEYMEKGNLMHVLKTQIDVPLSLKGRIIVEAIEGMCYLHDKGVIHKDLKPENILVDRDFHIKIADLGVASFKTWSKLTKEKDNKQKEVSSTTKKNNGGTLYYMAPEHLNDINAKPTEKSDVYSFGIVLWAIFAKKEPYENVICTEQFVICIKSGNRPNVEEILEYCPREIISLMERCWQAIPEDRPTFLGIEEEFRPFYLSHFEEYVEEDVASLKKEYPDQSPVLQRMFSLQHDCVPLPPSRSNSEQPGSLHSSQGLQMGPVEESWFSSSPEYPQDENDRSVQAKLQEEASYHAFGIFAEKQTKPQPRQNEAYNREEERKRRVSHDPFAQQRARENIKSAGARGHSDPSTTSRGIAVQQLSWPATQTVWNNGLYNQHGFGTTGTGVWYPPNLSQMYSTYKTPVPETNIPGSTPTMPYFSGPVADDLIKYTIFNSSGIQIGNHNYMDVGLNSQPPNNTCKEESTSRHQAIFDNTTSLTDEHLNPIRENLGRQWKNCARKLGFTESQIDEIDHDYERDGLKEKVYQMLQKWLMREGTKGATVGKLAQALHQCCRIDLLNHLIRASQS

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
			G49108TO	GlyGen The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

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Pathway Name	Organism
TNFR1-induced NF-kappa-B signaling pathway	Mus musculus
TNFR1-induced proapoptotic signaling	Mus musculus
TRIF-mediated programmed cell death	Mus musculus
Ub-specific processing proteases	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

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Other Information

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Summary

External Links

Annotation

International Collaboration

Acknowledgements