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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Neprilysin
Summary
- UniProt ID
- Q61391
- Gene Symbol
-
- Mme
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- 3D-structure
- Cell membrane
- Direct protein sequencing
- Disulfide bond
- Glycoprotein
- Metal-binding
- Metalloprotease
- Myristate
- Phosphoprotein
- Reference proteome
- Signal-anchor
- Transmembrane helix
- Zinc
- Gene Ontology (GO)
| GO Term |
|---|
| replicative senescence |
| amyloid-beta clearance |
| amyloid-beta clearance by cellular catabolic process |
| positive regulation of long-term synaptic potentiation |
| GO Term |
|---|
| membrane raft |
| early endosome |
| trans-Golgi network |
| brush border |
| synaptic vesicle |
| cytoplasm |
| plasma membrane |
| membrane |
| axon |
| synapse |
Sequence
MGRSESQMDITDINAPKPKKKQRWTPLEISLSVLVLLLTIIAVTMIALYATYDDGICKSSDCIKSAARLIQNMDASVEPCTDFFKYACGGWLKRNVIPETSSRYSNFDILRDELEVILKDVLQEPKTEDIVAVQKAKTLYRSCINESAIDSRGGQPLLKLLPDIYGWPVASDNWDQTYGTSWTAEKSIAQLNSKYGKKVLINFFVGTDDKNSTQHIIHFDQPRLGLPSRDYYECTGIYKEACTAYVDFMISVARLIRQEQSLPIDENQLSLEMNKVMELEKEIANATTKPEDRNDPMLLYNKMTLAKLQNNFSLEVNGKSFSWSNFTNEIMSTVNINIQNEEEVVVYAPEYLTKLKPILTKYSPRDLQNLMSWRFIMDLVSSLSRNYKESRNAFRKALYGTTSETATWRRCANYVNGNMENAVGRLYVEAAFAGESKHVVEDLIAQIREVFIQTLDDLTWMDAETKKKAEEKALAIKERIGYPDDIISNENKLNNEYLELNYREDEYFENIIQNLKFSQSKQLKKLREKVDKDEWISGAAVVNAFYSSGRNQIVFPAGILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKDGDLVDWWTQQSANNFKDQSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGIGQAYRAYQNYVKKNGEEKLLPGLDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRIIGTLQNSAEFADAFHCRKNSYMNPERKCRVW
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 145 | N-linked (GlcNAc...) asparagine | |||
| 211 | N-linked (GlcNAc...) asparagine | |||
| 285 | N-linked (GlcNAc...) asparagine | |||
| 311 | N-linked (GlcNAc...) asparagine | |||
| 325 | N-linked (GlcNAc...) asparagine |
|
||
| 628 | N-linked (GlcNAc...) asparagine |
|
||
|
|
G42124LM
G06110VR
G80920RR
G31936TA
G70619PT
G13933DE
G28589EC
G78920EP
G88761JB
G23505EP
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Metabolism of Angiotensinogen to Angiotensins | Mus musculus |
| Neutrophil degranulation | Mus musculus |
| Physiological factors | Mus musculus |
