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Nucleophosmin

Summary

UniProt ID

Q61937

Gene Symbol

Npm1

Organism

Mus musculus (house mouse)

External Links

GlyGen: Q61937
PubChem: Q61937
The O-GlcNAc Database: Q61937
RaftProt: Q61937
O-GlcNAcAtlas: Q61937

Annotation

Keyword

3D-structure
ADP-ribosylation
Acetylation
Chaperone
Cytoskeleton
DNA-binding
Direct protein sequencing
Disulfide bond
Isopeptide bond
Nucleus
Phosphoprotein
RNA-binding
Reference proteome
Ubl conjugation

Gene Ontology (GO)

Displaying entries **1 - 10** of 44 in total

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GO Term
positive regulation of DNA-templated transcription
positive regulation of transcription by RNA polymerase II
protein stabilization
regulation of cell growth
DNA repair
protein localization
positive regulation of cell population proliferation
negative regulation of cell population proliferation
post-transcriptional regulation of gene expression
negative regulation of gene expression

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GO Term
nucleoplasm
cytosol
nucleus
nucleolus
cytoplasm
centrosome
nuclear matrix
granular component
small ribosomal subunit
large ribosomal subunit

Displaying entries **1 - 10** of 16 in total

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GO Term
chromatin binding
unfolded protein binding
p53 binding
DNA binding
RNA binding
ATP binding
rRNA binding
enzyme binding
histone binding
identical protein binding

Annotation information from UniProt.

Sequence

MEDSMDMDMSPLRPQNYLFGCELKADKDYHFKVDNDENEHQLSLRTVSLGAGAKDELHIVEAEAMNYEGSPIKVTLATLKMSVQPTVSLGGFEITPPVVLRLKCGSGPVHISGQHLVAVEEDAESEDEDEEDVKLLGMSGKRSAPGGGNKVPQKKVKLDEDDEDDDEDDEDDEDDDDDDFDEEETEEKVPVKKSVRDTPAKNAQKSNQNGKDLKPSTPRSKGQESFKKQEKTPKTPKGPSSVEDIKAKMQASIEKGGSLPKVEAKFINYVKNCFRMTDQEAIQDLWQWRKSL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 4** entries
Position	GlyTouCan ID	Source
75	G49108TO	The O-GlcNAc Database
82	G49108TO	The O-GlcNAc Database
86		GlyGen
88	G49108TO	GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 5** entries
Pathway Name	Organism
Deposition of new CENPA-containing nucleosomes at the centromere	Mus musculus
PKR-mediated signaling	Mus musculus
SUMOylation of transcription cofactors	Mus musculus
TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation	Mus musculus
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain	Mus musculus