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Discoidin domain-containing receptor 2

Summary

UniProt ID

Q62371

Gene Symbol

Ddr2
Ntrkr3
Tkt
Tyro10

Organism

Mus musculus (house mouse)

External Links

PubChem: Q62371

Annotation

Keyword

ATP-binding
Cell membrane
Disulfide bond
Glycoprotein
Osteogenesis
Phosphoprotein
Receptor
Reference proteome
Signal
Transmembrane helix
Tyrosine-protein kinase

Gene Ontology (GO)

Displaying entries **1 - 10** of 32 in total

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GO Term
collagen fibril organization
regulation of bone mineralization
biomineral tissue development
positive regulation of collagen biosynthetic process
regulation of tissue remodeling
negative regulation of apoptotic process
positive regulation of osteoblast differentiation
positive regulation of protein kinase activity
positive regulation of fibroblast proliferation
positive regulation of extracellular matrix disassembly

Displaying **all 3** entries
GO Term
actin cytoskeleton
receptor complex
apical plasma membrane

Displaying **all 4** entries
GO Term
ATP binding
protein tyrosine kinase collagen receptor activity
transmembrane receptor protein tyrosine kinase activity
collagen binding

Annotation information from UniProt.

Sequence

MIPIPRMPLVLLLLLLILGSAKAQVNPAICRYPLGMSGGHIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVQPDDLKEFLQIDLRTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGSRWISWRNRHGKQVLDGNSNPYDVFLKDLEPPIVARFVRLIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGFIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPTAVYFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSGALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSESSMFNNNRSSSPSEQESNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPAQPNGPEGVPHYAEADIVNLQGVTGGNTYCVPAVTMDLLSGKDVAVEEFPRKLLAFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIRLLAVCITEDPLCMITEYMENGDLNQFLSRHEPLSSCSSDATVSYANLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQIYLPQPALCPDSVYKLMLSCWRRETKHRPSFQEIHLLLLQQGAE

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 5** entries
Position	Description	Source
121	N-linked (GlcNAc...) asparagine	UniProt
213	N-linked (GlcNAc...) asparagine	UniProt
261	N-linked (GlcNAc...) asparagine	UniProt
280	N-linked (GlcNAc...) asparagine	UniProt
372	N-linked (GlcNAc...) asparagine	UniProt