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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Receptor tyrosine-protein kinase erbB-3
Summary
- UniProt ID
- Q62799
- Gene Symbol
-
- Erbb3
- Organism
- Rattus norvegicus (Norway rat)
External Links
- PubChem
- Q62799
Annotation
- Keyword
-
- ATP-binding
- Disulfide bond
- Glycoprotein
- Phosphoprotein
- Receptor
- Reference proteome
- Signal
- Transmembrane helix
- Tyrosine-protein kinase
- Gene Ontology (GO)
| GO Term |
|---|
| response to xenobiotic stimulus |
| positive regulation of glucose import |
| epidermal growth factor receptor signaling pathway |
| ERBB2-ERBB3 signaling pathway |
| extrinsic apoptotic signaling pathway in absence of ligand |
Sequence
MRATGTLQVLCFLLSLARGSEMGNSQAVCPGTLNGLSVTGDADNQYQTLYKLYEKCEVVMGNLEIVLTGHNADLSFLQWIREVTGYVLVAMNEFSVLPLPNLRVVRGTQVYDGKFAIFVMLNYNTNSSHALRQLKFTQLTEILSGGVYIEKNDKLCHMDTIDWRDIVRVRGAEIVVKNNGANCPPCHEVCKGRCWGPGPDDCQILTKTICAPQCNGRCFGPNPNQCCHDECAGGCSGPQDTDCFACRRFNDSGACVPRCPEPLVYNKLTFQLEPNPHTKYQYGGVCVASCPHNFVVDQTFCVRACPPDKMEVDKHGLKMCEPCGGLCPKACEGTGSGSRYQTVDSSNIDGFVNCTKILGNLDFLITGLNVDPWHKIPALDPEKLNVFRTVREITGYLNIQSWPPHMHNFSVFSNLTTIGGRSLYNRGFSLLIMKNLNVTSLGFRSLKEISAGRVYISANQQLCYHHSLNWTRLLRGPSEERLDIKYDRPLGECLAEGKVCDPLCSSGGCWGPGPGQCLSCRNYSREGVCVTHCNFLQGEPREFVHEAQCFSCHPECLPMEGTSTCNGSGSDACARCAHFRDGPHCVNSCPHGILGAKGPIYKYPDAQNECRPCHENCTQGCNGPELQDCLGQAEVLMSKPHLVIAVTVGLAVILMILGGSFLYWRGRRIQNKRAMRRYLERGESIEPLDPSEKANKVLARIFKETELRKLKVLGSGVFGTVHKGIWIPEGESIKIPVCIKVIEDKSGRQSFQAVTDHMLAVGSLDHAHIVRLLGLCPGSSLQLVTQYLPLGSLLDHVKQHRETLGPQLLLNWGVQIAKGMYYLEEHSMVHRDLALRNVMLKSPSQVQVADFGVADLLPPDDKQLLHSEAKTPIKWMALESIHFGKYTHQSDVWSYGVTVWELMTFGAEPYAGLRLAEIPDLLEKGERLAQPQICTIDVYMVMVKCWMIDENIRPTFKELANEFTRMARDPPRYLVIKRASGPGTPPAAEPSVLTTKELQEAELEPELDLDLDLEAEEEGLATSLGSALSLPTGTLTRPRGSQSLLSPSSGYMPMNQSSLGEACLDSAVLGGREQFSRPISLHPIPRGRPASESSEGHVTGSEAELQEKVSVCRSRSRSRSPRPRGDSAYHSQRHSLLTPVTPLSPPGLEEEDGNGYVMPDTHLRGASSSREGTLSSVGLSSVLGTEEEDEDEEYEYMNRKRRGSPPRPPRPGSLEELGYEYMDVGSDLSASLGSTQSCPLHPMAIVPSAGTTPDEDYEYMNRRRGAGGAGGDYAAMGACPAAEQGYEEMRAFQGPGHHAPHVRYARLKTLRSLEATDSAFDNPDYWHSRLFPKANAQRT
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 126 | N-linked (GlcNAc...) asparagine |
|
||
| 250 | N-linked (GlcNAc...) asparagine |
|
||
| 353 | N-linked (GlcNAc...) asparagine |
|
||
| 408 | N-linked (GlcNAc...) asparagine |
|
||
| 414 | N-linked (GlcNAc...) asparagine |
|
||
| 437 | N-linked (GlcNAc...) asparagine |
|
||
| 469 | N-linked (GlcNAc...) asparagine |
|
||
| 522 | N-linked (GlcNAc...) asparagine |
|
||
| 566 | N-linked (GlcNAc...) asparagine |
|
||
| 616 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Downregulation of ERBB2 signaling | Rattus norvegicus |
| Downregulation of ERBB2:ERBB3 signaling | Rattus norvegicus |
| ERBB2 Activates PTK6 Signaling | Rattus norvegicus |
| ERBB2 Regulates Cell Motility | Rattus norvegicus |
| GRB7 events in ERBB2 signaling | Rattus norvegicus |
| PI3K events in ERBB2 signaling | Rattus norvegicus |
| PI3K/AKT Signaling | Rattus norvegicus |
| PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling | Rattus norvegicus |
| RAF/MAP kinase cascade | Rattus norvegicus |
| SHC1 events in ERBB2 signaling | Rattus norvegicus |
