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von Willebrand factor (Fragment)
Summary
- UniProt ID
- Q62935
- Gene Symbol
-
- Vwf
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- Blood coagulation
- Cell adhesion
- Disulfide bond
- Extracellular matrix
- Glycoprotein
- Reference proteome
- Repeat
- Gene Ontology (GO)
| GO Term |
|---|
| collagen-containing extracellular matrix |
| endoplasmic reticulum |
| external side of plasma membrane |
| Weibel-Palade body |
| extracellular region |
| extracellular space |
| GO Term |
|---|
| positive regulation of intracellular signal transduction |
| inflammatory response |
| cell adhesion |
| blood coagulation |
| hemostasis |
| platelet activation |
| liver development |
| response to immobilization stress |
| liver regeneration |
| placenta development |
| GO Term |
|---|
| protease binding |
| integrin binding |
| collagen binding |
| immunoglobulin binding |
| identical protein binding |
| protein-folding chaperone binding |
Sequence
HCDGVNLTCEACQEPGGLVVPPTDAPVSSTTPYVEDTPEPPLHNFYCSKLLDLVFLLDGSYRLSEAEFEVLKAFVVGTMERLHISQKRIRVAVVEYHDGSHAYLELRARKRPSELRRIASQIKYVGSQLASTSEVLKYTLFQIFGKIDRPEASRVILLLTASQEPQRMARYFTRYLQGFKKKKVILIPVGIGPHANLKQIRLIEKQAPENKAFLLSGVDELEQRRDEIINYLCDLAPEAPAPSKPPQVAHITVSPGISGVSSPGPKRKSLVLDVVFVLEASDEVGEANFNKSKEFLEEVIQRMDVSPAGTHIAVLQYSYTVNVEYTFKEAQSKEDVLRHVREIRYQGGNRTNTGQALQYLSEHSFSPSQGDREQAPNLVYMVTGNPASDEIRRLPGDIQVVPIGVGSRANLQELERISRPITPIFIQDFE
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 6 | N-linked (GlcNAc...) asparagine |
|
||
| 23 | O-linked (GalNAc...) threonine |
|
||
| 30 | O-linked (GalNAc...) threonine |
|
||
| 31 | O-linked (GalNAc...) threonine |
|
||
| 252 | O-linked (GalNAc...) threonine |
|
||
| 261 | O-linked (GalNAc...) serine |
|
||
| 290 | N-linked (GlcNAc...) asparagine |
|
||
| 349 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:224 | transient cerebral ischemia |
