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MIRAGE
Sonic hedgehog protein
Summary
- UniProt ID
- Q63673
- Gene Symbol
-
- Shh
- Vhh-1
- Gene ID
- 29499
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- Autocatalytic cleavage
- Calcium
- Cell membrane
- Developmental protein
- Endoplasmic reticulum
- Glycoprotein
- Golgi apparatus
- Metal-binding
- Palmitate
- Protease
- Reference proteome
- Signal
- Transferase
- Zinc
- Gene Ontology (GO)
| GO Term |
|---|
| hippocampal mossy fiber to CA3 synapse |
| extracellular space |
| plasma membrane |
| membrane |
| axon |
| dendrite |
| extracellular matrix |
| neuronal cell body |
| presynapse |
| postsynapse |
| GO Term |
|---|
| glycosaminoglycan binding |
| peptidase activity |
| patched binding |
| laminin-1 binding |
| calcium ion binding |
| zinc ion binding |
| cholesterol-protein transferase activity |
Sequence
MLLLLARCFLVALASSLLVCPGLACGPGRGFGKRQHPKKLTPLAYKQFIPNVAEKTLGASGRYEGKITRNSERFKELTPNYNPDIIFKDEENTGADRLMTQRCKDKLNALAISVMNQWPGVKLRVTEGWDEDGHHSEESLHYEGRAVDITTSDRDRSKYGMLARLAVEAGFDWVYYESKARIHCSVKAENSVAAKSDGCFPGSATVHLEQGGTKLVKDLSPGDRVLAADDQGRLLYSDFLTFLDRDEGAKKVFYVIETREPRERLLLTAAHLLFVAPHNDSGPTPGPSPLFASRVRPGQRVYVVAERGGDRRLLPAAVHSVTLREEAAGAYAPLTADGTILINRVLASCYAVIEEHSWAHRAFAPFRLAHALLAALAPARTDGGGGGSIPAPQSVAEARGAGPPAGIHWYSQLLYHIGTWLLDSETLHPLGMAVKSS
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 279 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Hedgehog ligand biogenesis | Rattus norvegicus |
| Ligand-receptor interactions | Rattus norvegicus |
| Release of Hh-Np from the secreting cell | Rattus norvegicus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0080855 | Parkinsonism | |
| DOID:5844 | myocardial infarction |
