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5-hydroxytryptamine receptor 1A

Summary

UniProt ID

Q64264

Gene Symbol

Htr1a
Gpcr18

Organism

Mus musculus (house mouse)

External Links

PubChem: Q64264

Annotation

Keyword

Behavior
Cell membrane
Cell projection
Disulfide bond
G-protein coupled receptor
Glycoprotein
Reference proteome
Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 10** of 18 in total

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GO Term
presynaptic modulation of chemical synaptic transmission
regulation of vasoconstriction
regulation of feeding behavior
behavioral fear response
G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
adenylate cyclase-inhibiting serotonin receptor signaling pathway
exploration behavior
adenylate cyclase-activating adrenergic receptor signaling pathway
NMDA glutamate receptor clustering
serotonin receptor signaling pathway

Displaying **all 6** entries
GO Term
plasma membrane
dendrite
neuronal cell body
GABA-ergic synapse
axon hillock
presynaptic membrane

Displaying **all 7** entries
GO Term
dopamine neurotransmitter receptor activity, coupled via Gs
G-protein alpha-subunit binding
G protein-coupled serotonin receptor activity
signaling receptor binding
serotonin binding
neurotransmitter receptor activity
receptor-receptor interaction

Annotation information from UniProt.

Sequence

MDMFSLGQGNNTTTSLEPFGTGGNDTGLSNVTFSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPEDRSNPNECTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKKGAGTSFGTSSAPPPKKSLNGQPGSGDCRRSAENRAVGTPCANGAVRQGEDDATLEVIEVHRVGNSKGHLPLPSESGATSYVPACLERKNERTAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSCHMPELLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCR

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 4** entries
Position	Description	Source
10	N-linked (GlcNAc...) asparagine	UniProt
11	N-linked (GlcNAc...) asparagine	UniProt
24	N-linked (GlcNAc...) asparagine	UniProt
30	N-linked (GlcNAc...) asparagine	UniProt