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MIRAGE
Unconventional myosin-VI
Summary
- UniProt ID
- Q64331
- Gene Symbol
-
- Myo6
- Sv
- Gene ID
- 17920
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- 3D-structure
- ATP-binding
- Actin-binding
- Calmodulin-binding
- Cell membrane
- Cell projection
- Coated pit
- Coiled coil
- Cytoplasm
- Cytoplasmic vesicle
- Deafness
- Disease variant
- Endocytosis
- Golgi apparatus
- Hearing
- Myosin
- Nucleus
- Phosphoprotein
- Protein transport
- Reference proteome
- Gene Ontology (GO)
| GO Term |
|---|
| plasma membrane |
| microvillus |
| vesicle membrane |
| axon |
| neuronal cell body |
| synapse |
| Golgi apparatus |
| cytosol |
| clathrin-coated vesicle |
| perinuclear region of cytoplasm |
| GO Term |
|---|
| actin filament binding |
| cytoskeletal motor activity |
| calmodulin binding |
| ATP binding |
Sequence
MEDGKPVWAPHPTDGFQMGNIVDIGPDSLTIEPLNQKGKTFLALINQVFPAEEDSKKDVEDNCSLMYLNEATLLHNVKVRYSKDRIYTYVANILIAVNPYFDIPKIYSSDTIKSYQGKSLGTMPPHVFAIADKAFRDMKVLKMSQSIIVSGESGAGKTENTKFVLRYLTESYGTGQDIDDRIVEANPLLEAFGNAKTVRNNNSSRFGKFVEIHFNEKSSVVGGFVSHYLLEKSRICVQGKEERNYHIFYRLCAGASEDIREKLHLSSPDNFRYLNRGCTRFFANKETDKQILQNRKSPEYVKAGSLKDPLLDDHGDFIRMCTAMKKIGLDDEEKLDLFRVVAGVLHLGNIDFEEAGSTSGGCNLKNKSAPSLEYCAELLGLDQDDLRVSLTTRVMLTTAGGTKGTVIKVPLKVEQANNARDALAKTVYSHLFDHVVNRVNQCFPFETSSYFIGVLDIAGFEYFEHNSFEQFCINYCNEKLQQFFNERILKEEQELYQKEGLGVNEVHYVDNQDCIDLIEVKLVGILDILDEENRLPQPSDQHFTSVVHQKHKDHFRLTIPRKSKLAVHRNLRDDEGFIIRHFAGAVCYETTQFVEKNNDALHMSLESLICESRDKFIRALFESSTNNNKDTKQKAGKLSFISVGNKFKTQLNLLLDKLRSTGASFIRCIKPNLKMTSHHFEGAQILSQLQCSGMVSVLDLMQGGFPSRASFHELYNMYKKYMPEKLARLDPRLFCKALFKALGLNEVDYKFGLTKVFFRPGKFAEFDQIMKSDPDHLAELVKRVNLWLVCSRWKKVQWCSLSVIKLKNKIKYRAEACIKMQKTIRMWLCKRRHKPRIDGLVKVGTLKKRLDKFNEVVSALKDGKPEVNRQIKNLEISIDALMAKIKSTMMTREQIQKEYDALVKSSEDLLSALQKKKQQEEEAERLRRIQEEMEKERKRREEDEERRRKEEEERRMKLEMEAKRKQEEEERKKREDDEKRIQAEVEAQLARQREEESQQQAVLAQECRDRELALRIAQNESELISDEAQGDMALRRGPAVQATKAAAGTKKHDLSKWKYAELRDTINTSCDIELLAACREEFHRRLKVYHAWKSKNKKRNTETEQRAPKSVTDYDFAPFLNNSPQQNPAAQLPARQQEIDMKRQQRFFRIPFIRPADQYKDPQNKKKGWWYAHFDGPWIARQMELHPDKPPILLVAGKDDMEMCELNLEETGLTRKRGAEILPRQFEEIWERCGGIQYLQSAIESRQARPTYATAMLQNLLK
Glycosylation Sites
G50166CH
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Gap junction degradation | Mus musculus |
| RHOBTB1 GTPase cycle | Mus musculus |
| RHOBTB2 GTPase cycle | Mus musculus |
| RHOU GTPase cycle | Mus musculus |
| Trafficking of AMPA receptors | Mus musculus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0110495 | autosomal recessive nonsyndromic deafness 37 | |
| DOID:0110552 | autosomal dominant nonsyndromic deafness 22 |
