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Sequestosome-1

Summary

UniProt ID

Q64337

Gene Symbol

Sqstm1
A170
STAP

Organism

Mus musculus (house mouse)

External Links

GlyGen: Q64337
PubChem: Q64337
RaftProt: Q64337

Annotation

Keyword

3D-structure
Acetylation
Alternative splicing
Apoptosis
Autophagy
Cytoplasm
Cytoplasmic vesicle
Differentiation
Endoplasmic reticulum
Endosome
Immunity
Isopeptide bond
Lysosome
Nucleus
Palmitate
Phosphoprotein
Reference proteome
Ubl conjugation
Zinc-finger

Gene Ontology (GO)

Displaying entries **21 - 30** of 30 in total

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GO Term
pexophagy
transcription by RNA polymerase II
endosome organization
protein catabolic process
negative regulation of protein ubiquitination
negative regulation of toll-like receptor 4 signaling pathway
regulation of canonical NF-kappaB signal transduction
regulation of protein complex stability
response to mitochondrial depolarisation
positive regulation of long-term synaptic potentiation

Displaying entries **11 - 15** of 15 in total

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GO Term
amphisome
phagophore assembly site
P-body
autophagosome
sperm midpiece

Displaying entries **1 - 10** of 16 in total

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GO Term
zinc ion binding
signaling receptor activity
ubiquitin-dependent protein binding
transcription coregulator activity
protein kinase C binding
protein-macromolecule adaptor activity
ubiquitin protein ligase binding
signaling adaptor activity
SH2 domain binding
identical protein binding

Annotation information from UniProt.

Sequence

MASFTVKAYLLGKEEATREIRRFSFCFSPEPEAEAQAAAGPGPCERLLSRVAVLFPTLRPGGFQAHYRDEDGDLVAFSSDEELTMAMSYVKDDIFRIYIKEKKECRREHRPPCAQEAPRNMVHPNVICDGCNGPVVGTRYKCSVCPDYDLCSVCEGKGLHREHSKLIFPNPFGHLSDSFSHSRWLRKLKHGHFGWPGWEMGPPGNWSPRPPRAGDGRPCPTAESASAPPEDPNVNFLKNVGESVAAALSPLGIEVDIDVEHGGKRSRLTPTTPESSSTGTEDKSNTQPSSCSSEVSKPDGAGEGPAQSLTEQMKKIALESVGQPEEQMESGNCSGGDDDWTHLSSKEVDPSTGELQSLQMPESEGPSSLDPSQEGPTGLKEAALYPHLPPEADPRLIESLSQMLSMGFSDEGGWLTRLLQTKNYDIGAALDTIQYSKHPPPL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
205			G37818NZ	GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 7** entries
Pathway Name	Organism
Interleukin-1 signaling	Mus musculus
KEAP1-NFE2L2 pathway	Mus musculus
NF-kB is activated and signals survival	Mus musculus
NRIF signals cell death from the nucleus	Mus musculus
PINK1-PRKN Mediated Mitophagy	Mus musculus
Pexophagy	Mus musculus
p75NTR recruits signalling complexes	Mus musculus