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Toll-like receptor 4

Summary

UniProt ID

Q68Y56

Gene Symbol

TLR4

Organism

Sus scrofa (pig)

External Links

PubChem: Q68Y56

Annotation

Keyword

Cell membrane
Cell projection
Disulfide bond
Endosome
Glycoprotein
Inflammatory response
Innate immunity
Leucine-rich repeat
NAD
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix

Gene Ontology (GO)

Displaying **all 8** entries
GO Term
positive regulation of NLRP3 inflammasome complex assembly
MyD88-dependent toll-like receptor signaling pathway
defense response to Gram-negative bacterium
detection of lipopolysaccharide
toll-like receptor 4 signaling pathway
inflammatory response
innate immune response
positive regulation of interleukin-1 beta production

Displaying **all 4** entries
GO Term
lipopolysaccharide receptor complex
ruffle
early endosome
plasma membrane

Displaying **all 4** entries
GO Term
transmembrane signaling receptor activity
NAD+ nucleotidase, cyclic ADP-ribose generating
lipopolysaccharide binding
lipopolysaccharide immune receptor activity

Annotation information from UniProt.

Sequence

MIPRIRLAVATIPAMAFLSCLRSESWDPCVQVVPNISYQCMELNFYKIPDNIPTSVKILDLSFNYLSHLDSNSFSSFPELQVLDLSRCEIQTIDDDAYQGLNYLSTLILTGNPIQSLALGAFSGLPSLQKLVAVETNLASLEDFPIGHLKTLNELNVAHNHIHSFKLPEYFSNLPNLEHLDLSKNKIENIYHEHLQVLHQVPLHNLSLDLSLNPLNFIEPGAFNKIRLNGLTLRSNFNSSDVMKTCIQGLAGSKVNQLVLGEFKNERNLESFDKSVLEELCNLTLEQFRIAHFGEFPDDVSDLFNCLANASVISLLSLNLHGLEALPNDFRWQHLEVVNCKLQQFPALKFNSLKKFVFKDNKHMHTFTEINLPNLQFLDLSGNHLSFKGCCSHNEFGTTKLKHLDLSFNEIITMKSNFMGLEQLEYLDFQHSSLKQANDFSIFLSLRNLHYLDISYTNIHVVFRGIFAGLVSLQTLKMAGNSFQNNLLPDVFTDLTNLILLDLSKCQLEQVSQRAFHSLPRLQVLNMSHNRLLFLDTLPYKPLHSLRILDCSYNLIVASKEQELQHLPRSLAFLNLTKNDFSCACEHQTFLQWVKDQKQLLVGAEQMVCTQPLEMQDLPVLSFRNATCQISEAVISASVLTFLLVSVAGILVYKFYFHLLLFVGCKKYGRGESTYDAFVIYSSQDEDWVRNELVKNLEEGVPPFHLCLHYRDFIPGVAIAANIIQEGFHKSRKVIVVVSQHFIQSRWCIFEYEIAQTWQFLRSHAGIIFIVLQKLEKSLLRQQVELYRLLSRNTYLEWEDSVLGRHIFWRRLKKALLDGKPWSPEGTEDSESNQHDTTAFT

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 8** entries
Position	Description	Source
35	N-linked (GlcNAc...) asparagine	UniProt
205	N-linked (GlcNAc...) asparagine	UniProt
238	N-linked (GlcNAc...) asparagine	UniProt
282	N-linked (GlcNAc...) asparagine	UniProt
309	N-linked (GlcNAc...) asparagine	UniProt
526	N-linked (GlcNAc...) asparagine	UniProt
575	N-linked (GlcNAc...) asparagine	UniProt
625	N-linked (GlcNAc...) asparagine	UniProt