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Alpha-2-macroglobulin-P

Summary

UniProt ID

Q6GQT1

Gene Symbol

A2m
A2mp

Organism

Mus musculus (house mouse)

External Links

GlycoProtDB: GPDB0005723
GlyGen: Q6GQT1
PubChem: Q6GQT1
The O-GlcNAc Database: Q6GQT1
O-GlcNAcAtlas: Q6GQT1

Annotation

Keyword

Bait region
Disulfide bond
Glycoprotein
Pregnancy
Reference proteome
Secreted
Serine protease inhibitor
Signal
Thioester bond

Gene Ontology (GO)

Displaying entries **1 - 10** of 11 in total

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GO Term
luteinization
female pregnancy
response to prostaglandin E
stem cell differentiation
response to glucocorticoid
embryonic liver development
negative regulation of complement activation, lectin pathway
acute inflammatory response to antigenic stimulus
response to nutrient
acute-phase response

Displaying 1 entry
GO Term
extracellular space

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GO Term
protease binding
signaling receptor binding
peptidase inhibitor activity
calcium-dependent protein binding
identical protein binding
brain-derived neurotrophic factor binding
endopeptidase inhibitor activity
serine-type endopeptidase inhibitor activity
interleukin-8 binding
interleukin-1 binding

Annotation information from UniProt.

Sequence

MGKRWLPSLALLPLPPPLLLLLLLLLPTNASAPQKPIYMVMVPSLLHAGTPEKGCLLFNHLNETVTVKVSMESVRGNQSLFTDLVVDKDLFHCASFIVPQSSSNEVMFLTVQVKGPTHEFRRRSTVLIKTKESLVFAQTDKPIYKPGQMVRFRVVSLDENFHPLNELIPLLYIQDSKKNRIAQWQNFRLEGGLKQLSFPLSSEPTQGSYKVVIRTESGRTVEHPFSVKEFVLPKFEVKVAVPETITILEEEMNVSVCGIYTYGKPVPGHVTVNICRKYSNPSSCFGEESLAFCEKFSQQLDGRGCFSQLVKTKSFQLKRQEYEMQLDVNAKIQEEGTGVEETGKGLTKITRTITKLSFVNVDTHFRQGIPFVGQVLLVDGRGTPIPYEMIFIGADEANQNINTTTDKNGLARFSINTDDIMGTSLTVRAKYKDSNVCYGFRWLTEENVEAWHTANAVFSPSRSFVHLESLPYKLRCEQTLAVQAHYILNDEAVLERKELVFYYLMMAKGGIVRAGTHVLPVTQGHKKGHFSILISMETDLAPVARLVLYTILPNGEVVGDTVKYEIEKCLANKVDLVFHPNIGLPATRAFLSVMASPQSLCGLRAVDQSVLLTKPEAELSASLVYDLLPVKDLTGFPKGVNQQEEDTNGCLKQNDTYINGILYSPVQNTNEEDMYGFLKDMGLKVFTNLNIRKPKVCERLGVNKIPAAYHLVSQGHMDAFLESSESPTETTRSYFPETWIWDLVIVDSTGVAEMEVTVPDTITEWKAGAFCLSNDTGLGLSPVIDFQAFQPFFVDLTMPYSVIRGEAFTLKATVLNYLQTCIRVGVQLEASPDFLATPEEKEQKSHCICMNERHTMSWAVIPKSLGNVNFTVSAEALDSKELCRNEVPVVPERGKKDTIIKSLLVEPEGLENEVTFNSLLCPTGAEVSEQISLKLPSDVVEESARASVTVLGDILGSAMQNTQDLLKMPYGCGEQNMVLFAPNIYVLDYLNETEQLTQEIKTKAITYLNTGYQRQLNYKHRDGSYSTFGDKPGRSHANTWLTAFVLKSFAQARRYIFIDESHITQALTWLSQQQKDNGCFRSSGSLLNNAMKGGVEDEVTLSAYITIALLEMSLPVTHPVVRNALFCLDTAWKSARRGASGNHVYTKALLAYAFALAGNQDTKKEILKSLDEEAVKEDNSVHWTRAQKPRVPADLWYQPQAPSAEVEMTAYVLLAYLTTELVPTREDLTAAMLIVKWLTKQQNSHGGFSSTQDTVVALHALSKYGAATFTRAKKAAHVTIQSSGAFYTKFQVNNDNQLLLQRVTLPTVPGDYTAKVAGEGCVYLQTSLKYSVLPREKEFPFALVVQTLPGTCEDLKAHTTFQISLNISYIGSRSDSNMAIADVKMVSGFIPLKPTVKMLERSVHVSRTEVSNNHVLIYLDKVSNQMLTLFFMVQQDIPVRDLKPAIVKVYDYYEKDEFAVAKYSAPCSAGYGNA

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

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Position	Description	GlyTouCan ID	Source
62	N-linked (GlcNAc...) asparagine	G80920RR	GlycoProtDB UniProt GlyGen
77	N-linked (GlcNAc...) asparagine	G80920RR	UniProt GlyGen
253	N-linked (GlcNAc...) asparagine		UniProt GlyGen
402	N-linked (GlcNAc...) asparagine		UniProt GlyGen
599		G49108TO	GlyGen
654	N-linked (GlcNAc...) asparagine		UniProt GlyGen
774	N-linked (GlcNAc...) asparagine		UniProt GlyGen
869	N-linked (GlcNAc...) asparagine	G80920RR	UniProt GlyGen
991	N-linked (GlcNAc...) asparagine		UniProt GlyGen
1026		G49108TO	GlyGen The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 4** entries
Pathway Name	Organism
Degradation of the extracellular matrix	Mus musculus
HDL assembly	Mus musculus
Intrinsic Pathway of Fibrin Clot Formation	Mus musculus
Platelet degranulation	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

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External Links

Annotation

International Collaboration

Acknowledgements