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Protein WWC2

Summary

UniProt ID: Q6NXJ0
Gene Symbol: Wwc2 D8Ertd594e MNCb-4173
Gene ID: 52357
Organism: Mus musculus (house mouse)

External Links

GlyGen: Q6NXJ0
The O-GlcNAc Database: Q6NXJ0
O-GlcNAcAtlas: Q6NXJ0
Re-Glyco: Q6NXJ0

Annotation

Keyword: Coiled coil Cytoplasm Phosphoprotein Reference proteome Repeat Repressor Transcription regulation

Gene Ontology (GO)

Displaying entries **1 - 5** of 16 in total

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GO Term	Evidence Code	Reference
negative regulation of transcription by RNA polymerase II	ISO	GO_REF
negative regulation of transcription by RNA polymerase II	IEA	GO_REF
regulation of transcription, DNA-templated	IBA	GO_REF
regulation of DNA-templated transcription	IBA	GO_REF
negative regulation of cell population proliferation	ISS	GO_REF

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

intracellular signal transduction [inference]

hippo signaling

cell motility [inference]

cell migration

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of hippo signaling

regulation of intracellular signal transduction [inference]

regulation of hippo signaling

negative regulation of hippo signaling

negative regulation of intracellular signal transduction [inference]

negative regulation of hippo signaling

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of hippo signaling

regulation of growth [inference]

negative regulation of growth [inference]

negative regulation of developmental growth [inference]

negative regulation of organ growth

regulation of developmental growth [inference]

regulation of organ growth [inference]

negative regulation of organ growth

negative regulation of developmental growth [inference]

negative regulation of organ growth

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of hippo signaling

negative regulation of growth [inference]

negative regulation of developmental growth [inference]

negative regulation of organ growth

negative regulation of cellular process [inference]

negative regulation of cell population proliferation

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of hippo signaling

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of hippo signaling

negative regulation of developmental process [inference]

negative regulation of developmental growth [inference]

negative regulation of organ growth

negative regulation of multicellular organismal process [inference]

negative regulation of organ growth

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of hippo signaling

regulation of intracellular signal transduction [inference]

regulation of hippo signaling

negative regulation of hippo signaling

negative regulation of intracellular signal transduction [inference]

negative regulation of hippo signaling

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of hippo signaling

regulation of developmental process [inference]

regulation of developmental growth [inference]

regulation of organ growth [inference]

negative regulation of organ growth

negative regulation of developmental growth [inference]

negative regulation of organ growth

negative regulation of developmental process [inference]

negative regulation of developmental growth [inference]

negative regulation of organ growth

regulation of cellular process [inference]

signal transduction [inference]

intracellular signal transduction [inference]

hippo signaling

regulation of cell communication [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of hippo signaling

regulation of intracellular signal transduction [inference]

regulation of hippo signaling

negative regulation of hippo signaling

negative regulation of intracellular signal transduction [inference]

negative regulation of hippo signaling

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of hippo signaling

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of cell population proliferation [inference]

negative regulation of cell population proliferation

negative regulation of cellular process [inference]

negative regulation of cell population proliferation

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of hippo signaling

regulation of multicellular organismal process [inference]

regulation of organ growth [inference]

negative regulation of organ growth

negative regulation of multicellular organismal process [inference]

negative regulation of organ growth

Displaying **all 5** entries
GO Term	Evidence Code	Reference
cytoplasm	ISO	GO_REF
cytoplasm	IBA	GO_REF
cytoplasm	IEA	GO_REF GO_REF
cytosol	ISO	GO_REF
cytosol	IEA	GO_REF GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	Reference
kinase binding	ISO	GO_REF
kinase binding	IBA	GO_REF
kinase binding	IEA	GO_REF
signaling adaptor activity	ISO	GO_REF
signaling adaptor activity	IEA	GO_REF

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

enzyme binding [inference]

kinase binding

molecular adaptor activity

protein-macromolecule adaptor activity [inference]

signaling adaptor activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MPRRAGSGQLPLPRGWEEARDYDGKVFYIDHNTRRTSWIDPRDRLTKPLSFADCVGDELPWGWEAGFDPQIGAYYIDHINKTTQIEDPRKQWRGEQEKMLKDYLSVAQDALRTQKELYHVKEQRLALALDEYVRLNDAYKEKSSSHTSLFSGSSSSTKYDPDILKAEISTTQLRVKKLKRELSHMKQELLYKQQGFETLQQIDEKMSGGQSGYELNEAKAILTELKSIRKAISSGEKEKQDLMQSLAKLQERFHLDQNMGSSEPDLRSSPVNSHLSLSRQTLDAGSQTSISGDIGVRSRSNLAEKVRLSLQYEEAKRSMANLKIELSKLDGEAWPGALDIEKEKLMLINEKEELLKELQFITPQKRSQEELERLEAERQHLEEELMAARGSPSRALTERLKLEEKRKELLQKLEETTKLTTSLYSQLQSLSSSTLSMSSGSSLGSLASSRGSLNTSSRGSLNSLSSSELYYSSQGDQMDTDYQYKLDFLLQEKGGYIPSGPITTIHENEVVKSPSQPGQSGLCGVGVTASSHTTPLTEASKSVASLSSRSSLSSLSPPGSPLVLDSVFPGSSHDTSPHQFPTDFEDCELSRRFADVGLGENQALLDSDSGGASQPLLEDKGLSDCPGELLCEGATDVEKSLPKRRGLHLRGDKTTRVSAAASDESVAGDSGVYEASMKQPGEMEDVPYSEEDVTIVETAQVQIGLRYDTKSSSFMVIIAQLRNLHAFSIPHSSKVYFRVALLPSSADVSCLFRTKVHPPTESVLYNDVFRVAVSQAALQQKTLRVDLCSASKHRREECLAGTQISLADLPFSNEIFMLWYNLLPSKQMPCKKNEDGNEEPGARSQQPMLDPIDLDAVSALLARTSAELLAVEQELAQEEEEEELRPERRGPGRDCLTMLREASDEPAALRESGVPLAEGSRCTEDPKPCPRGPETSQCRKEPAEDPGQLPSGLPTLVDKETNTDEVVDSNMAVRPKDRSSLSSRQHPFVRNSVIVRSQTFSPGERSQYICRLNRSDSDSSTLAKKSLFVRNSTERRSLRVKRAVCQPTLRRTAQECPVRTSLDLELDLQASLTRQSRLNDELQALRGLRQKLEELKAQGETDLPPGVLEDERFQKLLKQAEKQAEQTKEEQKQDLNAERLMRQVSKDVCRLREQSQKEPRQVQSFREKIAYFTRAKISIPSLPADDV

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 7** entries
Position	PubMed ID	GlyTouCan ID	Source
454		G28622XL	GlyGen
504		G49108TO	GlyGen
513	22517741 22645316 34678516 36852467 40021952 40885482	G49108TO	The O-GlcNAc Database
515	22517741 22645316 34678516 36852467 40021952 40885482	G49108TO	The O-GlcNAc Database
520	22517741 22645316 34678516 36852467 40021952 40885482	G49108TO	GlyGen The O-GlcNAc Database
528	22517741 22645316 34678516 36852467 40021952 40885482	G49108TO	GlyGen The O-GlcNAc Database
1031		G02815KT	GlyGen