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MIRAGE
Eukaryotic translation initiation factor 4 gamma 1
Summary
- UniProt ID
- Q6NZJ6
- Gene Symbol
-
- Eif4g1
- Gene ID
- 208643
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Acetylation
- Alternative splicing
- Cytoplasm
- Initiation factor
- Methylation
- Nucleus
- Phosphoprotein
- RNA-binding
- Reference proteome
- Translation regulation
- Gene Ontology (GO)
| GO Term |
|---|
| nucleus |
| cytoplasm |
| ribosome |
| postsynapse |
| cytosol |
| cytoplasmic stress granule |
| eukaryotic translation initiation factor 4F complex |
| GO Term |
|---|
| mRNA binding |
| translation initiation factor activity |
| ATP binding |
| eukaryotic initiation factor 4E binding |
Sequence
MNKAPQPTGPPPARSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQGGFRSLQHFYPSRAQPPSSAASRVQSAAPARPGPAPHVYPAGSQVMMIPSQISYSASQGAYYIPGQGRSTYVVPTQQYPVQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPASVAPAPVLMNQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGSLEPQPNGESPQVAVIIRPDDRSQGAAIGGRPGLPGPEHSPGTESQPSSPSPTPSPPPILEPGSESNLGVLSIPGDTMTTGMIPMSVEESTPISCETGEPYCLSPEPTLAEPILEVEVTLSKPIPESEFSSSPLQVSTALVPHKVETHEPNGVIPSEDLEPEVESSTEPAPPPLSPCASESLVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKKVSSAALASILSPAPPVAPSDTSPAQEEEMEEDDDDEEGGEAESEKGGEDVPLDSTPVPAQLSQNLEVAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEVDPAVPEVENQPPTGSNPSPESEGSMVPTQPEETEETWDSKEDKIHNAENIQPGEQKYEYKSDQWKPLNLEEKKRYDREFLLGFQFIFASMQKPEGLPHITDVVLDKANKTPLRQLDPSRLPGINCGPDFTPSFANLGRPALSNRGPPRGGPGGELPRGPAGLGPRRSQQGPRKETRKIISSVIMTEDIKLNKAEKAWKPSSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKDDDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDFAKAKPRMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRQSNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSDKRRGGPPGPPINRGLPLVDDGGWNTVPISKGSRPIDTSRLTKITKPGSIDSNNQLFAPGGRLSWGKGSSGGSGAKPSDTASEATRPATLNRFSALQQTLPAENTDNRRVVQRSSLSRERGEKAGDRGDRLERSERGGDRGDRLDRARTPATKRSFSKEVEERSRERPSQPEGLRKAASLTEDRGRDPVKREATLPPVSPPKAALSVDEVEKKSKAIIEEYLHLNDMKEAVQCVQELASPSLLFIFVRLGIESTLERSTIAREHMGRLLHQLLCAGHLSTAQYYQGLYETLELAEDMEIDIPHVWLYLAELITPILQEDGVPMGELFREITKPLRPMGKATSLLLEILGLLCKSMGPKKVGMLWREAGLSWREFLAEGQDVGSFVAEKKVEYTLGEESEAPGQRTLAFEELRRQLEKLLKDGGSNQRVFDWIDANLNEQQIASNTLVRALMTTVCYSAIIFETPLRVDVQVLKVRARLLQKYLCDEQKELQALYALQALVVTLEQPANLLRMFFDALYDEDVVKEDAFYSWESSKDPAEQQGKGVALKSVTAFFNWLREAEDEESDHN
Glycosylation Sites
G49108TO
G72747WU
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| AUF1 (hnRNP D0) binds and destabilizes mRNA | Mus musculus |
| Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S | Mus musculus |
| Deadenylation of mRNA | Mus musculus |
| GTP hydrolysis and joining of the 60S ribosomal subunit | Mus musculus |
| ISG15 antiviral mechanism | Mus musculus |
| L13a-mediated translational silencing of Ceruloplasmin expression | Mus musculus |
| Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) | Mus musculus |
| Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) | Mus musculus |
| Ribosomal scanning and start codon recognition | Mus musculus |
| Translation initiation complex formation | Mus musculus |
