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Tyrosine-protein phosphatase non-receptor type substrate 1

Summary

UniProt ID: Q6P6I8
Gene Symbol: Sirpa Bit Myd1 Ptpns1 Shps1 Sirp
Gene ID: 19261
Organism: Mus musculus (house mouse)

External Links

GlycoProtDB: GPDB0005783
RaftProt: Q6P6I8
Re-Glyco: Q6P6I8

Annotation

Keyword: Disulfide bond Glycoprotein Immunoglobulin domain Repeat SH3-binding Signal Transmembrane helix

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	Reference
regulation of interleukin-6 production	IEA	GO_REF
regulation of tumor necrosis factor production	IEA	GO_REF
regulation of nitric oxide biosynthetic process	IEA	GO_REF
negative regulation of phagocytosis	IEA	GO_REF
myeloid leukocyte migration	IEA	GO_REF

GO Hierarchy

biological process

immune system process [inference]

leukocyte migration [inference]

myeloid leukocyte migration

cellular process [inference]

cell motility [inference]

cell migration [inference]

leukocyte migration [inference]

myeloid leukocyte migration

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of transport [inference]

negative regulation of transport [inference]

negative regulation of endocytosis [inference]

negative regulation of phagocytosis

regulation of vesicle-mediated transport [inference]

regulation of endocytosis [inference]

negative regulation of endocytosis [inference]

negative regulation of phagocytosis

regulation of phagocytosis [inference]

negative regulation of phagocytosis

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of cellular component organization [inference]

negative regulation of endocytosis [inference]

negative regulation of phagocytosis

negative regulation of transport [inference]

negative regulation of endocytosis [inference]

negative regulation of phagocytosis

regulation of cellular process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

regulation of interleukin-6 production

regulation of tumor necrosis factor superfamily cytokine production [inference]

regulation of tumor necrosis factor production

regulation of nitric oxide biosynthetic process

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

regulation of interleukin-6 production

regulation of tumor necrosis factor superfamily cytokine production [inference]

regulation of tumor necrosis factor production

regulation of nitric oxide metabolic process [inference]

regulation of nitric oxide biosynthetic process

negative regulation of cellular process [inference]

negative regulation of cellular component organization [inference]

negative regulation of endocytosis [inference]

negative regulation of phagocytosis

regulation of cellular component organization [inference]

regulation of endocytosis [inference]

negative regulation of endocytosis [inference]

negative regulation of phagocytosis

regulation of phagocytosis [inference]

negative regulation of phagocytosis

negative regulation of cellular component organization [inference]

negative regulation of endocytosis [inference]

negative regulation of phagocytosis

regulation of vesicle-mediated transport [inference]

regulation of endocytosis [inference]

negative regulation of endocytosis [inference]

negative regulation of phagocytosis

regulation of phagocytosis [inference]

negative regulation of phagocytosis

regulation of multicellular organismal process [inference]

regulation of cytokine production [inference]

regulation of interleukin-6 production

regulation of tumor necrosis factor superfamily cytokine production [inference]

regulation of tumor necrosis factor production

Displaying 1 entry
GO Term	Evidence Code	Reference
membrane	IEA	GO_REF GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane

Displaying **all 2** entries
GO Term	Evidence Code	Reference
SH3 domain binding
protein phosphatase binding	IEA	GO_REF

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

enzyme binding [inference]

phosphatase binding [inference]

protein phosphatase binding

protein domain specific binding [inference]

SH3 domain binding

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MEPAGPAPGRLGPLLLCLLLSASCFCTGATGKELKVTQPEKSVSVAAGDSTVLNCTLTSLLPVGPIRWYRGVGPSRLLIYSFAGEYVPRIRNVSDTTKRNNMDFSIRISNVTPADAGIYYCVKFQKGSSEPDTEIQSGGGTEVYVLAKPSPPEVSGPADRGIPDQKVNFTCKSHGFSPRNITLKWFKDGQELHPLETTVNPSGKNVSYNISSTVRVVLNSMDVNSKVICEVAHITLDRSPLRGIANLSNFIRVSPTVKVTQQSPTSMNQVNLTCRAERFYPEDLQLIWLENGNVSRNDTPKNLTKNTDGTYNYTSLFLVNSSAHREDVVFTCQVKHDQQPAITRNHTVLGFAHSSDQGSMQTFPDNNATHNWNVFIGVGVACALLVVLLMAALYLLRIKQKKAKGSTSSTRLHEPEKNAREITQIQDTNDINDITYADLNLPKEKKPAPRAPEPNNHTEYASIETGKVPRPEDTLTYADLDMVHLSRAQPAPKPEPSFSEYASVQVQRK

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites