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Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas

Summary

UniProt ID

Q6R0H7

Gene Symbol

Gnas
Gnas1

Organism

Mus musculus (house mouse)

External Links

GlyGen: Q6R0H7
PubChem: Q6R0H7
The O-GlcNAc Database: Q6R0H7
RaftProt: Q6R0H7

Annotation

Keyword

ADP-ribosylation
Alternative splicing
Cell membrane
Coiled coil
GTP-binding
Magnesium
Metal-binding
Phosphoprotein
Reference proteome
Transducer

Gene Ontology (GO)

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GO Term
regulation of transcription by RNA polymerase II
response to xenobiotic stimulus
negative regulation of blood pressure
adenylate cyclase-activating G protein-coupled receptor signaling pathway
skeletal system development
tissue homeostasis
positive regulation of protein phosphorylation
endochondral ossification
energy reserve metabolic process
G protein-coupled receptor signaling pathway

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GO Term
cytosol
ruffle
endosome
heterotrimeric G-protein complex
COPI-coated Golgi to ER transport vesicle
perinuclear region of cytoplasm
recycling endosome
cytoplasm
plasma membrane
membrane

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GO Term
metal ion binding
protein domain specific binding
G-protein beta-subunit binding
G-protein beta/gamma-subunit complex binding
beta-2 adrenergic receptor binding
D1 dopamine receptor binding
mu-type opioid receptor binding
corticotropin-releasing hormone receptor 1 binding
alpha-tubulin binding
alkylglycerophosphoethanolamine phosphodiesterase activity

Annotation information from UniProt.

Sequence

MGCLGNSKTEDQRNEEKAQREANKKIEKQLQKDKQVYRATHRLLLLGAGESGKSTIVKQMRILHVNGFNGEGGEEDPQAARSNSDGEKATKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDYILSVMNVPNFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQADYVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASSSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLRQYELL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
163			G62765YT	GlyGen
			G49108TO	GlyGen The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 6** entries
Pathway Name	Organism
G alpha (s) signalling events	Mus musculus
GPER1 signaling	Mus musculus
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion	Mus musculus
Glucagon-type ligand receptors	Mus musculus
Prostacyclin signalling through prostacyclin receptor	Mus musculus
Vasopressin regulates renal water homeostasis via Aquaporins	Mus musculus