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NPC1-like intracellular cholesterol transporter 1

Summary

UniProt ID

Q6T3U3

Gene Symbol

Npc1l1

Organism

Rattus norvegicus (Norway rat)

External Links

PubChem: Q6T3U3

Annotation

Keyword

3D-structure
Cell membrane
Cholesterol metabolism
Disulfide bond
Glycoprotein
Reference proteome
Signal
Transmembrane helix
Transport

Gene Ontology (GO)

Displaying entries **1 - 10** of 11 in total

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GO Term
lipoprotein metabolic process
cholesterol import
intestinal cholesterol absorption
cholesterol biosynthetic process
response to xenobiotic stimulus
cholesterol homeostasis
vitamin transport
response to muscle activity
cholesterol transport
vitamin E metabolic process

Displaying **all 3** entries
GO Term
plasma membrane
apical plasma membrane
brush border membrane

Displaying **all 7** entries
GO Term
lipid transporter activity
heterocyclic compound binding
cholesterol binding
myosin V binding
protein homodimerization activity
vitamin E binding
small GTPase binding

Annotation information from UniProt.

Sequence

MAAAWLGWLLWALLLSAAQGELYTPKHEAGVCTFYEECGKNPELSGGLTSLSNVSCLSNTPARHVTGEHLALLQRICPRLYNGPNTTFACCSTKQLLSLESSMSITKALLTRCPACSDNFVSLHCHNTCSPDQSLFINVTRVVERGAGEPPAVVAYEAFYQRSFAEKAYESCSQVRIPAAASLAVGSMCGVYGSALCNAQRWLNFQGDTGNGLAPLDITFHLLEPGQALPDGIQPLNGKIAPCNESQGDDSAVCSCQDCAASCPVIPPPEALRPSFYMGRMPGWLALIIIFTAVFVLLSAVLVRLRVVSNRNKNKAEGPQEAPKLPHKHKLSPHTILGRFFQNWGTRVASWPLTVLALSFIVVIALAAGLTFIELTTDPVELWSAPKSQARKEKSFHDEHFGPFFRTNQIFVTARNRSSYKYDSLLLGSKNFSGILSLDFLLELLELQERLRHLQVWSPEAERNISLQDICYAPLNPYNTSLSDCCVNSLLQYFQNNRTLLMLTANQTLNGQTSLVDWKDHFLYCANAPLTFKDGTSLALSCMADYGAPVFPFLAVGGYQGTDYSEAEALIITFSLNNYPADDPRMAQAKLWEEAFLKEMESFQRNTSDKFQVAFSAERSLEDEINRTTIQDLPVFAVSYIIVFLYISLALGSYSRCSRVAVESKATLGLGGVIVVLGAVLAAMGFYSYLGVPSSLVIIQVVPFLVLAVGADNIFIFVLEYQRLPRMPGEQREAHIGRTLGSVAPSMLLCSLSEAICFFLGALTPMPAVRTFALTSGLAIILDFLLQMTAFVALLSLDSKRQEASRPDVLCCFSTRKLPPPKEKEGLLLRFFRKIYAPFLLHRFIRPVVMLLFLTLFGANLYLMCNINVGLDQELALPKDSYLIDYFLFLNRYLEVGPPVYFVTTSGFNFSSEAGMNATCSSAGCKSFSLTQKIQYASEFPDQSYVAIAASSWVDDFIDWLTPSSSCCRLYIRGPHKDEFCPSTDTSFNCLKNCMNRTLGPVRPTAEQFHKYLPWFLNDPPNIRCPKGGLAAYRTSVNLSSDGQVIASQFMAYHKPLRNSQDFTEALRASRLLAANITADLRKVPGTDPNFEVFPYTISNVFYQQYLTVLPEGIFTLALCFVPTFVVCYLLLGLDMCSGILNLLSIIMILVDTIGLMAVWGISYNAVSLINLVTAVGMSVEFVSHITRSFAVSTKPTRLERAKDATVFMGSAVFAGVAMTNFPGILILGFAQAQLIQIFFFRLNLLITLLGLLHGLVFLPVVLSYLGPDVNQALVQEEKLASEAAVAPEPSCPQYPSPADADANVNYGFAPELAHGANAARSSLPKSDQKF

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying entries **1 - 10** of 17 in total

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Position	Description	Source
53	N-linked (GlcNAc...) asparagine	UniProt
85	N-linked (GlcNAc...) asparagine	UniProt
138	N-linked (GlcNAc...) asparagine	UniProt
244	N-linked (GlcNAc...) asparagine	UniProt
416	N-linked (GlcNAc...) asparagine	UniProt
431	N-linked (GlcNAc...) asparagine	UniProt
464	N-linked (GlcNAc...) asparagine	UniProt
479	N-linked (GlcNAc...) asparagine	UniProt
497	N-linked (GlcNAc...) asparagine	UniProt
506	N-linked (GlcNAc...) asparagine	UniProt