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NPC1-like intracellular cholesterol transporter 1

Summary

UniProt ID

Q6T3U3

Gene Symbol

Npc1l1

Gene ID

432367

Organism

Rattus norvegicus (Norway rat)

External Links

PubChem: Q6T3U3
Re-Glyco: Q6T3U3

Annotation

Keyword

3D-structure
Cell membrane
Cholesterol metabolism
Disulfide bond
Glycoprotein
Reference proteome
Signal
Transmembrane helix
Transport

Gene Ontology (GO)

Displaying **all 3** entries
GO Term
plasma membrane
apical plasma membrane
brush border membrane

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying entries **1 - 10** of 12 in total

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GO Term
vitamin E metabolic process
sterol transport
cholesterol import
response to xenobiotic stimulus
response to muscle activity
cholesterol transport
lipoprotein metabolic process
cholesterol homeostasis
cholesterol biosynthetic process
intestinal cholesterol absorption

Displaying **all 7** entries
GO Term
lipid transporter activity
protein homodimerization activity
small GTPase binding
vitamin E binding
cholesterol binding
myosin V binding
heterocyclic compound binding

Annotation information from UniProt.

Sequence

MAAAWLGWLLWALLLSAAQGELYTPKHEAGVCTFYEECGKNPELSGGLTSLSNVSCLSNTPARHVTGEHLALLQRICPRLYNGPNTTFACCSTKQLLSLESSMSITKALLTRCPACSDNFVSLHCHNTCSPDQSLFINVTRVVERGAGEPPAVVAYEAFYQRSFAEKAYESCSQVRIPAAASLAVGSMCGVYGSALCNAQRWLNFQGDTGNGLAPLDITFHLLEPGQALPDGIQPLNGKIAPCNESQGDDSAVCSCQDCAASCPVIPPPEALRPSFYMGRMPGWLALIIIFTAVFVLLSAVLVRLRVVSNRNKNKAEGPQEAPKLPHKHKLSPHTILGRFFQNWGTRVASWPLTVLALSFIVVIALAAGLTFIELTTDPVELWSAPKSQARKEKSFHDEHFGPFFRTNQIFVTARNRSSYKYDSLLLGSKNFSGILSLDFLLELLELQERLRHLQVWSPEAERNISLQDICYAPLNPYNTSLSDCCVNSLLQYFQNNRTLLMLTANQTLNGQTSLVDWKDHFLYCANAPLTFKDGTSLALSCMADYGAPVFPFLAVGGYQGTDYSEAEALIITFSLNNYPADDPRMAQAKLWEEAFLKEMESFQRNTSDKFQVAFSAERSLEDEINRTTIQDLPVFAVSYIIVFLYISLALGSYSRCSRVAVESKATLGLGGVIVVLGAVLAAMGFYSYLGVPSSLVIIQVVPFLVLAVGADNIFIFVLEYQRLPRMPGEQREAHIGRTLGSVAPSMLLCSLSEAICFFLGALTPMPAVRTFALTSGLAIILDFLLQMTAFVALLSLDSKRQEASRPDVLCCFSTRKLPPPKEKEGLLLRFFRKIYAPFLLHRFIRPVVMLLFLTLFGANLYLMCNINVGLDQELALPKDSYLIDYFLFLNRYLEVGPPVYFVTTSGFNFSSEAGMNATCSSAGCKSFSLTQKIQYASEFPDQSYVAIAASSWVDDFIDWLTPSSSCCRLYIRGPHKDEFCPSTDTSFNCLKNCMNRTLGPVRPTAEQFHKYLPWFLNDPPNIRCPKGGLAAYRTSVNLSSDGQVIASQFMAYHKPLRNSQDFTEALRASRLLAANITADLRKVPGTDPNFEVFPYTISNVFYQQYLTVLPEGIFTLALCFVPTFVVCYLLLGLDMCSGILNLLSIIMILVDTIGLMAVWGISYNAVSLINLVTAVGMSVEFVSHITRSFAVSTKPTRLERAKDATVFMGSAVFAGVAMTNFPGILILGFAQAQLIQIFFFRLNLLITLLGLLHGLVFLPVVLSYLGPDVNQALVQEEKLASEAAVAPEPSCPQYPSPADADANVNYGFAPELAHGANAARSSLPKSDQKF

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying entries **1 - 10** of 17 in total

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Position	Description	Source
53	N-linked (GlcNAc...) asparagine	UniProt
85	N-linked (GlcNAc...) asparagine	UniProt
138	N-linked (GlcNAc...) asparagine	UniProt
244	N-linked (GlcNAc...) asparagine	UniProt
416	N-linked (GlcNAc...) asparagine	UniProt
431	N-linked (GlcNAc...) asparagine	UniProt
464	N-linked (GlcNAc...) asparagine	UniProt
479	N-linked (GlcNAc...) asparagine	UniProt
497	N-linked (GlcNAc...) asparagine	UniProt
506	N-linked (GlcNAc...) asparagine	UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying 1 entry
Pathway Name	Organism
Intestinal lipid absorption	Rattus norvegicus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

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External Links

Annotation

International Collaboration

Acknowledgements