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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
CD109 antigen
Summary
- UniProt ID
- Q6YHK3
- Gene Symbol
-
- CD109
- CPAMD7
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- Alternative splicing
- Bait region
- Cell membrane
- Direct protein sequencing
- Disulfide bond
- GPI-anchor
- Reference proteome
- Serine protease inhibitor
- Signal
- Thioester bond
- Gene Ontology (GO)
| GO Term |
|---|
| extracellular region |
| extracellular space |
| plasma membrane |
| platelet alpha granule membrane |
| cytosol |
| cell surface |
| side of membrane |
| GO Term |
|---|
| serine-type endopeptidase inhibitor activity |
| transforming growth factor beta binding |
Sequence
MQGPPLLTAAHLLCVCTAALAVAPGPRFLVTAPGIIRPGGNVTIGVELLEHCPSQVTVKAELLKTASNLTVSVLEAEGVFEKGSFKTLTLPSLPLNSADEIYELRVTGRTQDEILFSNSTRLSFETKRISVFIQTDKALYKPKQEVKFRIVTLFSDFKPYKTSLNILIKDPKSNLIQQWLSQQSDLGVISKTFQLSSHPILGDWSIQVQVNDQTYYQSFQVSEYVLPKFEVTLQTPLYCSMNSKHLNGTITAKYTYGKPVKGDVTLTFLPLSFWGKKKNITKTFKINGSANFSFNDEEMKNVMDSSNGLSEYLDLSSPGPVEILTTVTESVTGISRNVSTNVFFKQHDYIIEFFDYTTVLKPSLNFTATVKVTRADGNQLTLEERRNNVVITVTQRNYTEYWSGSNSGNQKMEAVQKINYTVPQSGTFKIEFPILEDSSELQLKAYFLGSKSSMAVHSLFKSPSKTYIQLKTRDENIKVGSPFELVVSGNKRLKELSYMVVSRGQLVAVGKQNSTMFSLTPENSWTPKACVIVYYIEDDGEIISDVLKIPVQLVFKNKIKLYWSKVKAEPSEKVSLRISVTQPDSIVGIVAVDKSVNLMNASNDITMENVVHELELYNTGYYLGMFMNSFAVFQECGLWVLTDANLTKDYIDGVYDNAEYAERFMEENEGHIVDIHDFSLGSSPHVRKHFPETWIWLDTNMGYRIYQEFEVTVPDSITSWVATGFVISEDLGLGLTTTPVELQAFQPFFIFLNLPYSVIRGEEFALEITIFNYLKDATEVKVIIEKSDKFDILMTSNEINATGHQQTLLVPSEDGATVLFPIRPTHLGEIPITVTALSPTASDAVTQMILVKAEGIEKSYSQSILLDLTDNRLQSTLKTLSFSFPPNTVTGSERVQITAIGDVLGPSINGLASLIRMPYGCGEQNMINFAPNIYILDYLTKKKQLTDNLKEKALSFMRQGYQRELLYQREDGSFSAFGNYDPSGSTWLSAFVLRCFLEADPYIDIDQNVLHRTYTWLKGHQKSNGEFWDPGRVIHSELQGGNKSPVTLTAYIVTSLLGYRKYQPNIDVQESIHFLESEFSRGISDNYTLALITYALSSVGSPKAKEALNMLTWRAEQEGGMQFWVSSESKLSDSWQPRSLDIEVAAYALLSHFLQFQTSEGIPIMRWLSRQRNSLGGFASTQDTTVALKALSEFAALMNTERTNIQVTVTGPSSPSPVKFLIDTHNRLLLQTAELAVVQPTAVNISANGFGFAICQLNVVYNVKASGSSRRRRSIQNQEAFDLDVAVKENKDDLNHVDLNVCTSFSGPGRSGMALMEVNLLSGFMVPSEAISLSETVKKVEYDHGKLNLYLDSVNETQFCVNIPAVRNFKVSNTQDASVSIVDYYEPRRQAVRSYNSEVKLSSCDLCSDVQGCRPCEDGASGSHHHSSVIFIFCFKLLYFMELWL
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 397 |
|
|||
| 403 |
|
|||
| 419 | N-linked (GlcNAc...) asparagine |
|
||
| 513 | N-linked (GlcNAc...) asparagine | |||
| 645 | N-linked (GlcNAc...) asparagine |
|
||
| 1042 |
|
|||
| 1086 | N-linked (GlcNAc...) asparagine | |||
| 1295 |
|
|||
| 1355 | N-linked (GlcNAc...) asparagine | |||
|
|
|
G16125XL
G68490OW
G80479JV
G07246CJ
G70441OD
G80920RR
G90659AW
G83633GK
G62765YT
G41247ZX
G49108TO
G70232NH
G57888GL
G13131HA
G37881RL
G80075MS
G11629QQ
G57776ZS
G86880BF
G85282JO
G87123QX
G79666IR
G81263BG
G92135MA
G22310AV
G45395BF
G59324HL
G10819WX
G40926MX
G14972EH
G43223CG
G08918WF
G00912UN
G27915IV
G87661QW
G83646BJ
G46691LC
G04657PL
G27058EU
G41071NU
G70619PT
G42124LM
G82443XX
G05962QB
G84452RH
G52096TR
G69031IF
G70888PK
G20312EM
G92406TI
G46503DX
G01650EU
G37399XV
G28541PG
G31852PQ
G02815KT
G92050GC
G06356OH
G59334JE
G10846ZT
G00273SJ
G83229XP
G27126ED
G60033FS
G72747WU
G59626AS
G65184UU
G10486CT
G20956ZV
G74724QE
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Platelet degranulation | Homo sapiens |
| Post-translational modification: synthesis of GPI-anchored proteins | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:1325 | bronchus cancer | |
| DOID:13515 | tuberous sclerosis | |
| DOID:1432 | blindness | |
| DOID:14323 | Marfan syndrome | |
| DOID:1612 | breast cancer | |
| DOID:162 | cancer | |
| DOID:1749 | squamous cell carcinoma | |
| DOID:1793 | pancreatic cancer | |
| DOID:1969 | cerebral palsy | |
| DOID:219 | colon cancer |
