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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
DNA replication ATP-dependent helicase/nuclease DNA2
Summary
- UniProt ID
- Q6ZQJ5
- Gene Symbol
-
- Dna2
- Dna2l
- Kiaa0083
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- 3D-structure
- 4Fe-4S
- Acetylation
- Alternative splicing
- DNA repair
- DNA replication
- DNA-binding
- Endonuclease
- Helicase
- Mitochondrion
- Multifunctional enzyme
- Nucleus
- Reference proteome
- Gene Ontology (GO)
| GO Term |
|---|
| cytoplasm |
| chromosome, telomeric region |
| mitochondrial nucleoid |
| nucleoplasm |
| gamma DNA polymerase complex |
| GO Term |
|---|
| metal ion binding |
Sequence
MEPLDELDLLLLEEDGGAEAVPRVELLRKKADALFPETVLSRGVDNRYLVLAVETSQNERGAEEKRLHVTASQDREHEVLCILRNGWSSVPVEPGDIVHLEGDCTSEPWIIDDDFGYFILYPDMMISGTSVASSIRCLRRAVLSETFRGSDPATRQMLIGTILHEVFQKAISESFAPERLQELALQTLREVRHLKEMYRLNLSQDEILCEVEEYLPSFSKWAEDFMRKGPSSEFPQMQLSLPSDGSNRSSPCNIEVVKSLDIEESIWSPRFGLKGKIDVTVGVKIHRDCKMKYKVMPLELKTGKESNSIEHRSQVVLYTLLSQERREDPEAGWLLYLKTGQMYPVPANHLDKRELLKLRNWLAASLLHRVSRAAPGEEARLSALPQIIEEEKTCKYCSQIGNCALYSRAVEEQGDDASIPEAMLSKIQEETRHLQLAHLKYFSLWCLMLTLESQSKDNRKTHQSIWLTPASELEESGNCVGNLVRTEPVSRVCDGQYLHNFQRKNGPMPATNLMAGDRIILSGEERKLFALSKGYVKKMNKAAVTCLLDRNLSTLPATTVFRLDREERHGDISTPLGNLSKLMESTDPSKRLRELIIDFREPQFIAYLSSVLPHDAKDTVANILKGLNKPQRQAMKRVLLSKDYTLIVGMPGTGKTTTICALVRILSACGFSVLLTSYTHSAVDNILLKLAKFKVGFLRLGQSHKVHPDIQKFTEEEICRSRSIASLAHLEELYNSHPIVATTCMGINHPIFSRKTFDFCIVDEASQISQPVCLGPLFFSRRFVLVGDHQQLPPLVVNREARALGMSESLFKRLERNESAVVQLTVQYRMNRKIMSLSNKLTYAGKLECGSDRVANAVLALPNLKDARLSLQLYADYSDSPWLAGVLEPDNPVCFLNTDKVPAPEQVENGGVSNVTEARLIVFLTSTFIKAGCSPSDIGVIAPYRQQLRIISDLLARSSVGMVEVNTVDKYQGRDKSLILVSFVRSNEDGTLGELLKDWRRLNVALTRAKHKLILLGSVSSLKRFPPLGTLFDHLNAEQLILDLPSREHESLSHILGDCQRD
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
|
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| G2/M DNA damage checkpoint | Mus musculus |
| HDR through Homologous Recombination (HRR) | Mus musculus |
| HDR through Single Strand Annealing (SSA) | Mus musculus |
| Homologous DNA Pairing and Strand Exchange | Mus musculus |
| Presynaptic phase of homologous DNA pairing and strand exchange | Mus musculus |
| Processing of DNA double-strand break ends | Mus musculus |
| Regulation of TP53 Activity through Phosphorylation | Mus musculus |
| Removal of the Flap Intermediate | Mus musculus |
| Removal of the Flap Intermediate from the C-strand | Mus musculus |
| Resolution of D-loop Structures through Holliday Junction Intermediates | Mus musculus |
