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Eukaryotic translation initiation factor 2 subunit 1
Summary
- UniProt ID
- Q6ZWX6
- Gene Symbol
-
- Eif2s1
- Eif2a
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Acetylation
- Cytoplasm
- Initiation factor
- Mitochondrion
- Phosphoprotein
- RNA-binding
- Reference proteome
- Translation regulation
- Gene Ontology (GO)
| GO Term |
|---|
| stress granule assembly |
| cellular response to amino acid starvation |
| regulation of translation in response to endoplasmic reticulum stress |
| PERK-mediated unfolded protein response |
| response to kainic acid |
| GO Term |
|---|
| RNA binding |
| ribosome binding |
| translation initiation factor activity |
Sequence
MPGLSCRFYQHKFPEVEDVVMVNVRSIAEMGAYVSLLEYNNIEGMILLSELSRRRIRSINKLIRIGRNECVVVIRVDKEKGYIDLSKRRVSPEEAIKCEDKFTKSKTVYSILRHVAEVLEYTKDEQLESLFQRTAWVFDDKYKRPGYGAYDAFKHAVSDPSILDSLDLNEDEREVLINNINRRLTPQAVKIRADIEVACYGYEGIDAVKEALRAGLNCSTETMPIKINLIAPPRYVMTTTTLERTEGLSVLNQAMAVIKEKIEEKRGVFNVQMEPKVVTDTDETELARQLERLERENAEVDGDDDAEEMEAKAED
Glycosylation Sites
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| ABC-family proteins mediated transport | Mus musculus |
| Cellular response to mitochondrial stress | Mus musculus |
| Formation of the ternary complex, and subsequently, the 43S complex | Mus musculus |
| GTP hydrolysis and joining of the 60S ribosomal subunit | Mus musculus |
| L13a-mediated translational silencing of Ceruloplasmin expression | Mus musculus |
| PERK regulates gene expression | Mus musculus |
| Recycling of eIF2:GDP | Mus musculus |
| Ribosomal scanning and start codon recognition | Mus musculus |
| Translation initiation complex formation | Mus musculus |
