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Toll-like receptor 6

Summary

UniProt ID

Q704V6

Gene Symbol

TLR6

Gene ID

407237

Organism

Bos taurus (domestic cattle)

External Links

PubChem: Q704V6
Re-Glyco: Q704V6

Annotation

Keyword

Cell membrane
Cytoplasmic vesicle
Disulfide bond
Glycoprotein
Golgi apparatus
Inflammatory response
Innate immunity
Leucine-rich repeat
NAD
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix

Gene Ontology (GO)

Displaying **all 5** entries
GO Term
phagocytic vesicle membrane
Toll-like receptor 2-Toll-like receptor 6 protein complex
plasma membrane
Golgi apparatus
membrane raft

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying **all 6** entries
GO Term
inflammatory response
innate immune response
toll-like receptor signaling pathway
positive regulation of interleukin-1 beta production
positive regulation of NLRP3 inflammasome complex assembly
cellular response to diacyl bacterial lipopeptide

Displaying **all 6** entries
GO Term
identical protein binding
NAD+ nucleotidase, cyclic ADP-ribose generating
Toll-like receptor 2 binding
signaling receptor activity
lipopeptide binding
transmembrane signaling receptor activity

Annotation information from UniProt.

Sequence

MIKDKESPIRSCHFVYIVALVFGTIIQFSDESEFVVDMSKTSLIHVPKDLPPKTKVLDLSQNNISELHLSDISFLSGLRVLRLSHNRIQGLDISIFKFNHDLEYLDLSHNQLQKISCHPITTTLKHLDLSFNDFDALPICKEFGNLTQLNFLGLSATKLQQLDLLPIAHLHLSCILLDLEDYMKENKKESLQILNTKKLHLVFHPNSFFSVQVDISANSLGCLQLTNIKLNDYNCQVLLKFLSGLTGGPTLLNFTLNHVETTWKCLVKVFQFLWPKPIEYLNIYNLTIVESIDEEVFTYYKTTLKALKIEHITNKVFIFSQTALYTVFSEMNILMLTISDTRFIHMLCPQEPSTFKFLNFTQNSFTDSVFQNCDTLARLETLILQKNELKDLFKTSLMTKDMLSLETLDVSWNSLEYDRSNGNCSWVGSIVVLNLSSNALTDSVFRCLPPRIKVLDLHNNRIRSIPKDVTGLETLQELNLASNSLAHLPGCGIFSSLSILIIEHNSISNPSADFFQSCQKIRSLKAGNNPFQCSCELRDFIQSVGQVSSDVVEGWPESYKCDYPESYKGTPLKDFQVSELSCNTALLIITIVVPGLVLAVAVTVLCIYLDLPWYLRMVCQWTQTRRRARNVPLEELQRTLQFHAFISYSEHDSAWVKNELIPNLEKEDIRICLHERNFVAGKSIVENIINCIEKSYKSIFVLSPNFVQSEWCHYELYFAHHNLFHEGSDNLILILLDPIPQYSIPSSYHKLRALMAQRTYLEWPKEKSKHGLFWANLRASINIKLMEKAAEIH

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 7** entries
Position	Description	Source
63	N-linked (GlcNAc...) asparagine	UniProt
145	N-linked (GlcNAc...) asparagine	UniProt
253	N-linked (GlcNAc...) asparagine	UniProt
285	N-linked (GlcNAc...) asparagine	UniProt
359	N-linked (GlcNAc...) asparagine	UniProt
423	N-linked (GlcNAc...) asparagine	UniProt
434	N-linked (GlcNAc...) asparagine	UniProt