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MIRAGE
Sodium- and chloride-dependent glycine transporter 2

Summary
UniProt ID
Q761V0
Gene Symbol
  • Glyt2
  • Slc6a5
Organism
Mus musculus (house mouse)
GlyGen
Q761V0
PubChem
Q761V0
O-GlcNAcAtlas
Q761V0
Re-Glyco
Q761V0
Annotation
Keyword
  • Alternative splicing
  • Cell membrane
  • Disulfide bond
  • Glycoprotein
  • Metal-binding
  • Neurotransmitter transport
  • Phosphoprotein
  • Reference proteome
  • Sodium
  • Symport
  • Transmembrane helix
Gene Ontology (GO)
Displaying all 3 entries
GO Term
presynapse
glycinergic synapse
plasma membrane
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying all 2 entries
GO Term
neurotransmitter reuptake
neurotransmitter uptake
Displaying all 2 entries
GO Term
metal ion binding
glycine:sodium symporter activity
Annotation information from UniProt.
Sequence
MDCSAPKEMNKQPANILEAAVPGHRDSPRAPRTSPEQDLPAEAPAATVQPPRVPRSASTGAQTFQSADARACEAQQSGVGFCNLSSPRAQATSAALRDLSEGHSAQANPPSGPAGAGNALHCKIPALRGPEEDANVSVGKGTLEHNNTPAVGWVNMSQSTVVLGTDGIASVLPGSVATTTIPEDEQGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLPIFFLEVSLGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSVLPWGSCNNPWNTPECKDKTKLLLDSCVIGDHPKIQIKNSTFCMTAYPNLTMVNFTSQTNKTFVSGSEEYFKYFVLKISAGIEYPGEIRWPLAFCLFLAWVIVYASLAKGIKSSGKVVYFTATFPYVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKVNIENVADQGPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHKPVFTLGCCICFFIMGFPMITQGGIYMFQLVDTYAASYALVIIAIFELVGISYVYGLQRFCEDIEMMIGFKPNIFWKVCWAFVTPTILTFILCFSFYQWEPMTYGSYRYPNWSMVLGWLMLACSVIWIPIMFVIKMYLAPGRFIERLKLVCSPQPDWGPFLAQHRGERYKNMIDPLGTSSLGLKLPVKDLELGTQC
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying all 9 entries
Position Description PubMed ID GlyTouCan ID Source
56
83
135
345 N-linked (GlcNAc...) asparagine
355 N-linked (GlcNAc...) asparagine
360 N-linked (GlcNAc...) asparagine
366 N-linked (GlcNAc...) asparagine
687
714 N-linked (GlcNAc...) asparagine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying 1 entry
Pathway Name Organism
Na+/Cl- dependent neurotransmitter transporters Mus musculus
Disease
Displaying 1 entry
DO ID Disease Name Source
DOID:0060698 hyperekplexia 3
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 8, 2025