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MIRAGE
Phosphatidylinositol-glycan biosynthesis class W protein
Summary
- UniProt ID
- Q7Z7B1
- Gene Symbol
-
- PIGW
- Gene ID
- 284098
- Organism
- Homo sapiens (human)
External Links
- PubChem
- Q7Z7B1
- The Human Metabolome Database
- HMDBP02977
- Re-Glyco
- Q7Z7B1
Annotation
- Keyword
-
- Acyltransferase
- Disease variant
- Endoplasmic reticulum
- GPI-anchor biosynthesis
- Glycoprotein
- Intellectual disability
- Phosphoprotein
- Reference proteome
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| endoplasmic reticulum membrane |
| GO Term |
|---|
| protein localization to plasma membrane |
| GPI anchor metabolic process |
| GPI anchor biosynthetic process |
| GO Term |
|---|
| O-acyltransferase activity |
| glucosaminyl-phosphatidylinositol O-acyltransferase activity |
Sequence
MSEKQMKEAFVSNLNGTTVLEITQGLCFPAFCILCRGFLIIFSQYLCSFSPTWKTRFLTDFVVLIVPMVATLTIWASFILLELLGVIIFGAGLLYQIYRRRTCYARLPFLKILEKFLNISLESEYNPAISCFRVITSAFTAIAILAVDFPLFPRRFAKTELYGTGAMDFGVGGFVFGSAMVCLEVRRRKYMEGSKLHYFTNSLYSVWPLVFLGIGRLAIIKSIGYQEHLTEYGVHWNFFFTIIVVKLITPLLLIIFPLNKSWIIALGITVLYQLALDFTSLKRLILYGTDGSGTRVGLLNANREGIISTLGYVAIHMAGVQTGLYMHKNRSHIKDLIKVACFLLLAAISLFISLYVVQVNVEAVSRRMANLAFCIWIVASSLILLSSLLLGDIILSFAKFLIKGALVPCSWKLIQSPVTNKKHSESLVPEAERMEPSLCLITALNRKQLIFFLLSNITTGLINLMVDTLHSSTLWALFVVNLYMFSNCLIVYVLYLQDKTVQFW
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 15 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Synthesis of glycosylphosphatidylinositol (GPI) | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0070432 | hyperphosphatasia with impaired intellectual development syndrome 5 |
