TIR domain-containing adapter molecule 1
| GO Term |
|---|
| mitochondrion |
| early endosome |
| cytosol |
| autophagosome |
| endosome membrane |
| ripoptosome |
| GO Term |
|---|
| protein kinase binding |
| signaling adaptor activity |
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 175 |
|
|||
| 603 |
|
|
| Pathway Name | Organism |
|---|---|
| Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) | Mus musculus |
| IKK complex recruitment mediated by RIP1 | Mus musculus |
| IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation | Mus musculus |
| Ligand-dependent caspase activation | Mus musculus |
| MyD88-independent TLR4 cascade | Mus musculus |
| Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7 | Mus musculus |
| TRAF6-mediated induction of TAK1 complex within TLR4 complex | Mus musculus |
| TRIF-mediated programmed cell death | Mus musculus |
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Supported by JST NBDC Grant Number JPMJND2204
Partly supported by NIH Common Fund Grant #1U01GM125267-01
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Last updated: December 8, 2025