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E3 ubiquitin-protein ligase Topors

Summary

UniProt ID

Q80Z37

Gene Symbol

Topors

Gene ID

106021

Organism

Mus musculus (house mouse)

External Links

GlyGen: Q80Z37
PubChem: Q80Z37
The O-GlcNAc Database: Q80Z37
O-GlcNAcAtlas: Q80Z37
Re-Glyco: Q80Z37

Annotation

Keyword

DNA damage
Isopeptide bond
Nucleus
Phosphoprotein
Reference proteome
Transferase
Ubl conjugation
Ubl conjugation pathway
Zinc-finger

Gene Ontology (GO)

Displaying **all 9** entries
GO Term
nuclear speck
gamma-tubulin complex
nucleus
ubiquitin ligase complex
spindle pole
centriole
PML body
photoreceptor connecting cilium
ciliary basal body

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying entries **1 - 10** of 12 in total

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GO Term
ubiquitin-dependent protein catabolic process
intrinsic apoptotic signaling pathway in response to DNA damage
protein localization to nucleus
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
proteasome-mediated ubiquitin-dependent protein catabolic process
protein K48-linked ubiquitination
protein monoubiquitination
protein sumoylation
maintenance of protein location in nucleus
DNA damage response

Displaying **all 7** entries
GO Term
antigen binding
ubiquitin-protein transferase activity
ubiquitin protein ligase activity
SUMO transferase activity
metal ion binding
DNA topoisomerase binding
DNA binding

Annotation information from UniProt.

Sequence

MGSQPPPPGSPLSREEGEAPPLVPAEEGRRRSRRVRLRGSCRHRPSLLSRRELASNGPAVPATASSEIMASAAKEFKMDNFSPKAGTSKLQQTVPADASPDSKCPICLDRFDNVSYLDRCLHKFCFRCVQEWSKNKAECPLCKQPFDSIFHSVRAEDDFKEYVLRPSYNGSFTNPEVRRFRYRTTMTRERSASLYSPSSTVSRRTTTPPDSGVLFEGLGISTRPRDVDIPQFMRQMALRGPTTTDERSLRKIQEQDIINFRRTLYRAGVRVRSIEDGGRYRDISAEFFRRNPACLHRLVPWLKRELTVLFGAHGSLVNIVQHIIMSNVTRYDLESQAFVSDLRPFLLNRTEHFIHEFISFARSPFNMAAFDQHANYDCPPSSEEGSRSDSSVITISPDEAETQELDMNASTVRQAPWDDETPGPSYSSSEQVHVGVSSLLNSSDSSDEELVSGGTTSQIQGVQTNDDVNNDSDSSSDNCVIVGFVKPLAERTPELVELSSDSEELGPYEKVETVKTQEQEQSYSSGDSDVSRASSPRSVLGKDEQMSKSHCDSDTRISSKKEEKRSTSLPAPRDSSSTRGDRVCSPYNHRHRKGGRSRSSDSRSQSRSGHDPRNHRKHGKKRLRNKRSRSRESSSRPRARKDKKRSRTRDSSWSRRSQTLSLSSGSTSRSRSRSSDHGKRRSRSRNRDRYYLRNNYGSKYKWEYTYYSRNKDRDGYESSYRRRTLSRAHYSRQSSSPEFRIQSFSERTNARKKNHSERKYYYYERRRSRSVSSNRSRTTSAGPDRVRNEKPGGKRKYKTRHLEGTSEEAQPAREFTSKGKDSHYQKSKLDGSYKNESDSFSDSRSSDRETKHKRRRRRTRSLSVEIVYEGKATDTSKHHKKKKKKHKKKHKKHHGDNTSRSPVVITIDSDSDGESEVKAGIECSNGSLPQPIQDGAFETKDVVTIEDELGVLDKDCDVTALADDLSTSQTVENCDSPAVPVEQTLDVREESTFASDLESQSSNVSIQAEPSRPVPSPRTSLSSVSPGRDCDVS

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites