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Beta-arrestin-1

Summary

UniProt ID

Q8BWG8

Gene Symbol

Arrb1

Gene ID

109689

Organism

Mus musculus (house mouse)

External Links

GlyGen: Q8BWG8
PubChem: Q8BWG8
The O-GlcNAc Database: Q8BWG8
Re-Glyco: Q8BWG8

Annotation

Keyword

Alternative splicing
Cell membrane
Cell projection
Coated pit
Cytoplasm
Cytoplasmic vesicle
Nucleus
Phosphoprotein
Protein transport
Reference proteome
Signal transduction inhibitor
Transcription regulation
Ubl conjugation

Gene Ontology (GO)

Displaying **all 6** entries
GO Term
nucleus
plasma membrane
cytoplasmic vesicle
cytosol
clathrin-coated pit
pseudopodium

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying entries **1 - 10** of 13 in total

1

2

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GO Term
positive regulation of protein binding
regulation of apoptotic process
negative regulation of Notch signaling pathway
negative regulation of cysteine-type endopeptidase activity
positive regulation of protein phosphorylation
positive regulation of receptor internalization
ubiquitin-dependent protein catabolic process
phototransduction
positive regulation of peptidyl-serine phosphorylation
positive regulation of insulin secretion involved in cellular response to glucose stimulus

Displaying **all 2** entries
GO Term
cysteine-type endopeptidase inhibitor activity involved in apoptotic process
mitogen-activated protein kinase kinase binding

Annotation information from UniProt.

Sequence

MGDKGTRVFKKASPNGKLTVYLGKRDFVDHIDLVDPVDGVVLVDPEYLKERRVYVTLTCAFRYGREDLDVLGLTFRKDLFVANVQSFPPAPEDKKPLTRLQERLIKKLGEHACPFTFEIPPNLPCSVTLQPGPEDTGKACGVDYEVKAFCAENLEEKIHKRNSVRLVIRKVQYAPERPGPQPTAETTRQFLMSDKPLHLEASLDKEIYYHGEPISVNVHVTNNTNKTVKKIKISVRQYADICLFNTAQYKCPVAMEEADDNVAPSSTFCKVYTLTPFLANNREKRGLALDGKLKHEDTNLASSTLLREGANREILGIIVSYKVKVKLVVSRGGLLGDLASSDVAVELPFTLMHPKPKEEPPHREVPESETPVDTNLIELDTNDDDIVFEDFARQRLKGMKDDKDEEDDGTGSPHLNNR

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
98			G49108TO	The O-GlcNAc Database
183				GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 10** entries
Pathway Name	Organism
Activation of SMO	Mus musculus
Cargo recognition for clathrin-mediated endocytosis	Mus musculus
Clathrin-mediated endocytosis	Mus musculus
G alpha (s) signalling events	Mus musculus
Golgi Associated Vesicle Biogenesis	Mus musculus
Lysosome Vesicle Biogenesis	Mus musculus
MAP2K and MAPK activation	Mus musculus
TGFBR3 regulates TGF-beta signaling	Mus musculus
Thrombin signalling through proteinase activated receptors (PARs)	Mus musculus
Ub-specific processing proteases	Mus musculus