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TGF-beta-activated kinase 1 and MAP3K7-binding protein 1

Summary

UniProt ID

Q8CF89

Gene Symbol

Tab1
Map3k7ip1

Organism

Mus musculus (house mouse)

External Links

GlyGen: Q8CF89
PubChem: Q8CF89
The O-GlcNAc Database: Q8CF89
O-GlcNAcAtlas: Q8CF89

Annotation

Keyword

3D-structure
Cytoplasm
Endoplasmic reticulum
Glycoprotein
Membrane
Phosphoprotein
Reference proteome
Ubl conjugation

Gene Ontology (GO)

Displaying **all 10** entries
GO Term
in utero embryonic development
heart morphogenesis
cardiac septum development
coronary vasculature development
lung development
aorta development
transforming growth factor beta receptor signaling pathway
non-canonical NF-kappaB signal transduction
positive regulation of MAPK cascade
positive regulation of cGAS/STING signaling pathway

Displaying **all 5** entries
GO Term
protein-containing complex
nuclear speck
cytosol
endoplasmic reticulum
endoplasmic reticulum membrane

Displaying **all 6** entries
GO Term
protein-containing complex binding
kinase activator activity
protein serine/threonine kinase activator activity
molecular adaptor activity
mitogen-activated protein kinase p38 binding
protein serine/threonine phosphatase activity

Annotation information from UniProt.

Sequence

MAAQRRSLLQSEQQPSWTDDLPLCHLSGVGSASNRSYSADGKGTESHPPEDNWLKFRSENNCFLYGVFNGYDGNRVTNFVAQRLSAELLLGQLNTEHTEADVRRVLLQAFDVVERSFLESIDDALAEKASLQSQLPEGVPQHQLPPQYQKILERLKALEREISGGAMAVVAVLLNSKLYVANVGTNRALLCKSTVDGLQVTQLNMDHTTENEDELFRLSQLGLDAGKIKQMGVICGQESTRRIGDYKVKYGYTDIDLLSAAKSKPIIAEPEIHGAQPLDGVTGFLVLMSEGLYKALEAAHGPGQANQEIAAMIDTEFAKQTSLDAVAQAVVDRVKRIHSDTFASGGERAKFCPRHEDMTLLVRNFGYPLGEMSQPTPTPAPGGRVYPVSVPYSSAQSTSKTSVTLSLVMPSQGQMVNGSHSASTLDEATPTLTNQSPTLTLQSTNTHTQSSSSSSDGGLFRSRPAHSLPPGEDGRVEPYVDFAEFYRLWSVDHGEQSVMTAP

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 6** entries
Position	Description	GlyTouCan ID	Source
389		G49108TO	GlyGen The O-GlcNAc Database
393	O-linked (GlcNAc) serine	G49108TO	UniProt GlyGen The O-GlcNAc Database
394		G49108TO	GlyGen The O-GlcNAc Database
397		G49108TO	GlyGen
398		G49108TO	GlyGen
399		G49108TO	GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying entries **1 - 10** of 13 in total

1

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Pathway Name	Organism
ALPK1 signaling pathway	Mus musculus
CLEC7A (Dectin-1) signaling	Mus musculus
FCERI mediated NF-kB activation	Mus musculus
IRAK2 mediated activation of TAK1 complex	Mus musculus
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation	Mus musculus
Interleukin-1 signaling	Mus musculus
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1	Mus musculus
NOD1/2 Signaling Pathway	Mus musculus
TAK1-dependent IKK and NF-kappa-B activation	Mus musculus
TNFR1-induced NF-kappa-B signaling pathway	Mus musculus