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Complement C1s-1 subcomponent
Summary
- UniProt ID
- Q8CFG8
- Gene Symbol
-
- C1s2
- C1s
- C1sb
- Gm5077
- Organism
- Mus musculus (house mouse)
External Links
- GlycoProtDB
- GPDB0006642
- PubChem
- Q8CFG8
Annotation
- Keyword
-
- Calcium
- Complement pathway
- Disulfide bond
- EGF-like domain
- Glycoprotein
- Hydroxylation
- Metal-binding
- Reference proteome
- Repeat
- Serine protease
- Signal
- Sushi
- Gene Ontology (GO)
| GO Term |
|---|
| proteolysis |
| innate immune response |
| complement activation, classical pathway |
| GO Term |
|---|
| extracellular region |
| extracellular space |
| GO Term |
|---|
| serine-type endopeptidase activity |
| calcium ion binding |
Sequence
MWYLVLFSLLASFSAEPTMHGEILSPNYPQAYPNDVVKSWDIEVPEGFGIHLYFTHVDIEPSESCAYDSVQIISGGIEEGRLCGQRTSKSPNSPIIEEFQFPYNKLQVVFTSDFSIEEQFTGFAAYYTAIDVNECTDFTDVPCSHFCNNFIGGYFCSCPPEYFLHDDMRNCGVNCSGDVFTALIGEISSPNYPNPYPENSRCEYQIQLQEGFQVVVTMQREDFDVEPADSEGNCPDSLTFAAKNQQFGPYCGDGFPGPLTIRTQSNTLGIVFQTDLMGQKKGWKLRYHGDPISCPKESTANSNWEPDKAKYVFKDVVKITCVDGFEVVEGHVSSTSYYSTCQSDGQWSNSGLKCQPVYCGIPDPIANGKVEEPENSVFGTVIHYTCEEPYYYMEHEEGGEYRCAANGRWVNDQLGIELPRCIPVCGVPTEPFQVQQKIFGGQPAKIENFPWQVFFNHPTAGGALINEYWVLTAAHVVEKNSDPSMYAGITALRLADLENAQRLYTKRVIIHPGWKEDDDLNPRTNFDNDIALVQLKDPVKMGPKFSPICLPGTSSEYNLSPGDMGLISGWGRTEKRLHVINLRGAKVPVTSLETCKQVKEENPTARPEDYVITDNMICAGEKGVDSCKGDSGGAFAFQVPNVKAPKFYVAGLVSWGKKCGAYGVYTKVKNYVDWILKTMQENSGPRKD
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 174 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Classical antibody-mediated complement activation | Mus musculus |
| Initial triggering of complement | Mus musculus |
| Regulation of Complement cascade | Mus musculus |
