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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Mannan-binding lectin serine protease 1
Summary
- UniProt ID
- Q8CHN8
- Gene Symbol
-
- Masp1
- Crarf
- Masp3
- Organism
- Rattus norvegicus (Norway rat)
External Links
- PubChem
- Q8CHN8
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Autocatalytic cleavage
- Calcium
- Complement activation lectin pathway
- Disulfide bond
- EGF-like domain
- Glycoprotein
- Hydroxylation
- Metal-binding
- Reference proteome
- Repeat
- Secreted
- Serine protease
- Signal
- Sushi
- Gene Ontology (GO)
| GO Term |
|---|
| complement activation |
| zymogen activation |
| complement activation, lectin pathway |
| GO Term |
|---|
| extracellular space |
| GO Term |
|---|
| serine-type endopeptidase activity |
| calcium ion binding |
| peptidase activity |
| protein homodimerization activity |
| calcium-dependent protein binding |
Sequence
MRFLSFRRLLLYHVLCLTLTEVSAHTVELNEMFGQIQSPGYPDSYPSDSEVTWNITVPEGFRVQLYFMHFNLESSYLCEYDYVKVETEDQVLATFCGRETTDTEQTPGQEVVLSPGSFMSVTFRSDFSNEERFTGFDAHYMAVDVDECKEREDEELSCDHYCHNYIGGYYCSCRFGYILHTDNRTCRVECSGNLFTQRTGTITSPDYPNPYPKSSECSYTIDLEEGFMVTLQFEDIFDIEDHPEVPCPYDYIKIKAGSKVWGPFCGEKSPEPISTQSHSIQILFRSDNSGENRGWRLSYRAAGNECPKLQPPVYGKIEPSQAVYSFKDQVLISCDTGYKVLKDNEVMDTFQIECLKDGAWSNKIPTCKIVDCGVPAVLKHGLVTFSTRNNLTTYKSEIRYSCQQPYYKMLHNTTGVYTCSAHGTWTNEVLKRSLPTCLPVCGLPKFSRKHISRIFNGRPAQKGTTPWIAMLSQLNGQPFCGGSLLGSNWVLTAAHCLHHPLDPEEPILHNSHLLSPSDFKIIMGKHWRRRSDEDEQHLHVKHIMLHPLYNPSTFENDLGLVELSESPRLNDFVMPVCLPEHPSTEGTMVIVSGWGKQFLQRLPENLMEIEIPIVNYHTCQEAYTPLGKKVTQDMICAGEKEGGKDACAGDSGGPMVTKDAERDQWYLVGVVSWGEDCGKKDRYGVYSYIYPNKDWIQRVTGVRN
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 54 | N-linked (GlcNAc...) asparagine |
|
||
| 183 | N-linked (GlcNAc...) asparagine |
|
||
| 390 | N-linked (GlcNAc...) asparagine |
|
||
| 412 | N-linked (GlcNAc...) asparagine |
|
||
| 538 | N-linked (GlcNAc...) asparagine |
|
||
| 604 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Ficolins bind to repetitive carbohydrate structures on the target cell surface | Rattus norvegicus |
| Initial triggering of complement | Rattus norvegicus |
| Lectin pathway of complement activation | Rattus norvegicus |
