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Scavenger receptor cysteine-rich domain-containing protein DMBT1

Summary

UniProt ID: Q8CIZ5
Gene Symbol: Dmbt1
Gene ID: 170568
Organism: Rattus norvegicus (Norway rat)

External Links

PubChem: Q8CIZ5
Re-Glyco: Q8CIZ5

Annotation

Keyword: Alternative splicing Cytoplasmic vesicle Developmental protein Differentiation Direct protein sequencing Disulfide bond Glycoprotein Phosphoprotein Protein transport Reference proteome Repeat Secreted Signal Transmembrane helix

Gene Ontology (GO)

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GO Term	Evidence Code	Reference
blastocyst development	ISO	GO_REF
inner cell mass cell proliferation	ISO	GO_REF
columnar/cuboidal epithelial cell differentiation
receptor-mediated endocytosis	ISO	GO_REF
defense response

GO Hierarchy

biological process

immune system process [inference]

immune response [inference]

humoral immune response [inference]

antimicrobial humoral response [inference]

antimicrobial humoral immune response mediated by antimicrobial peptide

cellular process [inference]

cell population proliferation [inference]

inner cell mass cell proliferation

vesicle-mediated transport [inference]

endocytosis [inference]

receptor-mediated endocytosis

cellular developmental process [inference]

cell differentiation

epithelial cell differentiation [inference]

columnar/cuboidal epithelial cell differentiation

developmental process [inference]

anatomical structure development [inference]

regeneration [inference]

tissue regeneration

animal gross anatomical part developmental process [inference]

cellular developmental process [inference]

cell differentiation

epithelial cell differentiation [inference]

columnar/cuboidal epithelial cell differentiation

growth [inference]

developmental growth [inference]

tissue regeneration

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to bacterium

defense response to bacterium [inference]

defense response to other organism [inference]

defense response to symbiont [inference]

antimicrobial humoral response [inference]

antimicrobial humoral immune response mediated by antimicrobial peptide

response to stimulus [inference]

response to stress [inference]

defense response

defense response to bacterium [inference]

defense response to other organism [inference]

defense response to symbiont [inference]

antimicrobial humoral response [inference]

antimicrobial humoral immune response mediated by antimicrobial peptide

immune response [inference]

humoral immune response [inference]

antimicrobial humoral response [inference]

antimicrobial humoral immune response mediated by antimicrobial peptide

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium

defense response to bacterium [inference]

defense response to other organism [inference]

defense response to symbiont [inference]

antimicrobial humoral response [inference]

antimicrobial humoral immune response mediated by antimicrobial peptide

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium

defense response to bacterium [inference]

defense response to other organism [inference]

defense response to symbiont [inference]

antimicrobial humoral response [inference]

antimicrobial humoral immune response mediated by antimicrobial peptide

response to endogenous stimulus [inference]

response to hormone [inference]

response to estrogen

response to chemical [inference]

response to hormone [inference]

response to estrogen

response to biphenyl

localization [inference]

macromolecule localization [inference]

intracellular protein localization [inference]

protein transport

establishment of localization [inference]

transport [inference]

protein transport

vesicle-mediated transport [inference]

endocytosis [inference]

receptor-mediated endocytosis

import into cell [inference]

endocytosis [inference]

receptor-mediated endocytosis

establishment of protein localization [inference]

protein transport

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell differentiation [inference]

positive regulation of epithelial cell differentiation

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of epithelial cell differentiation

regulation of developmental process [inference]

regulation of cell differentiation [inference]

regulation of epithelial cell differentiation [inference]

positive regulation of epithelial cell differentiation

positive regulation of cell differentiation [inference]

positive regulation of epithelial cell differentiation

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of epithelial cell differentiation

regulation of multicellular organismal development [inference]

regulation of epithelial cell differentiation [inference]

positive regulation of epithelial cell differentiation

regulation of cellular process [inference]

regulation of cell differentiation [inference]

regulation of epithelial cell differentiation [inference]

positive regulation of epithelial cell differentiation

positive regulation of cell differentiation [inference]

positive regulation of epithelial cell differentiation

positive regulation of cellular process [inference]

positive regulation of cell differentiation [inference]

positive regulation of epithelial cell differentiation

regulation of multicellular organismal process [inference]

regulation of multicellular organismal development [inference]

regulation of epithelial cell differentiation [inference]

positive regulation of epithelial cell differentiation

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GO Term	Evidence Code	Reference
obsolete extracellular space
cytoplasm	ISO	GO_REF
transport vesicle membrane	IEA	GO_REF
phagocytic vesicle membrane	ISO	GO_REF
extracellular matrix	ISS	GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

cytoplasm

membrane [inference]

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

transport vesicle membrane

endocytic vesicle membrane [inference]

phagocytic vesicle membrane

secretory granule membrane [inference]

zymogen granule membrane

bounding membrane of organelle [inference]

transport vesicle membrane

endocytic vesicle membrane [inference]

phagocytic vesicle membrane

secretory granule membrane [inference]

zymogen granule membrane

external encapsulating structure [inference]

extracellular matrix

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GO Term	Evidence Code	Reference
lipopolysaccharide binding	ISO	GO_REF
DNA binding	ISO	GO_REF
scavenger receptor activity	ISO	GO_REF
scavenger receptor activity	IBA	GO_REF
zymogen binding	ISS	GO_REF

GO Hierarchy

molecular function

binding [inference]

nucleic acid binding [inference]

DNA binding

protein binding [inference]

enzyme binding [inference]

zymogen binding

lipid binding [inference]

lipopolysaccharide binding

small molecule binding [inference]

ion binding [inference]

anion binding [inference]

carboxylic acid binding [inference]

heparan sulfate binding

organic acid binding [inference]

carboxylic acid binding [inference]

heparan sulfate binding

carbohydrate derivative binding [inference]

lipopolysaccharide binding

glycosaminoglycan binding [inference]

heparan sulfate binding

lipoteichoic acid binding

sulfur compound binding [inference]

heparan sulfate binding

cargo receptor activity [inference]

scavenger receptor activity

molecular transducer activity [inference]

signaling receptor activity [inference]

pattern recognition receptor activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MGISIVIFEICLLWGQILSTASQSRSSTPDWWNHGGTINDVIYDTQETPEVTTTQVPDSTSIGTDSGLAVRLVNGGDRCRGRVEILYQGSWGTMCDDGTDSGLAVRLVNGGDRCRGRVEILYQGSWGTMCDDSWDINDANVVCRQLGCGWALSAPGSAQFGQGLGPIVLDDVACRGHEAYLWSCSHRGWLSHNCGHQEDAGVICSDSQTSSPTPGWWNPGGTNNDVIYDTQETTETSQTSSPTPDWWNHGGTINDVIYDTQETTEGTDSGLAVRLVNGGDRCRGRVEILYQGSWGTVCDDSWDINDANVVCRQLGCGWALSAPGSAQFGQGSGSIVLDDVACRGHEAYLWSCSHRGWLSHNCGHQEDAGVICSYSQTSSPTPDSQTSSPTPGWWNPGGTNNDVSYGPEQTTDATDSGLAVRLVNGGDRCQGRVEILYQGSWGTVCDDSWDTKDANVVCRQLVCGWALSAPGSAHFGQGSGSIVLDDVACTGHEAYLWSCSHRGWLSHNCGHHEDAGVICSDAQTQSTTWPDMWPTTTPETTTDWWTTKYSSSVPTTQFPTIADWWTTPSPEYTCGGLLTLPYGQFSSPYYPGSYPNNARCLWKIFVSSMNRVTVVFTDVQLEGGCNYDYILVFDGPENNSSLIARVCDGFNGSFTSTQNFMSVVFITDGSVTRRGFQADYYSTPISTSTTSPTTFPIVTDWWTTPSPEYTCGGLLTLPYGQFSSPYYPGSYPNNARCLWKIFVPSMNRVTVVFTDVQLEGGCNYDYILGFDGPEYNSSLIARVCDGSNGSFTSTQNFMSVVFITDGSVTRRGFQADYYSTPIRTSTTPPTTFPIITGNDSSLVLRLVNGTNRCEGRVEILYRGSWVPCADDSWDINDANVVCRQLGCGSALSAPGNAWFGQGSGLIVLDDVSCSGYESHLWNCRHPGWLVHNCRHVEDAGVICSLPDPTPSPGPVWTSPPFVNYTCGGFLTGLSGQFSSPYYPGSYPNNARCLWNIEVPNNYRVTVVFRDVQLEGGCNYDYIEIFDGPHHSSPLIARVCDGAMGSFTSTSNFMSVRFTTDHSVTRRGFRADYYSDFDNNTTNLLCLSNHMRASVSRSYLQSMGYSSRDLVIPGWNVSYQCQPQITQREVIFTIPYTGCGTTKQADNETINYSNFLKAAVSNGIIKRRKDLHIHVSCKMLQNTWVNTMYITNNTVEIQEVQYGNFDVNISFYTSSSFLYPVTSSPYYVDLDQNLYLQAEVLHSDTSLALFVDTCVASPHPNDFSSLTYDLIRSGCIRDETYQSYSSPSPRITRFKFSSFHFLNRFPSVYLQCKLVVCRANDVSSRCYRGCVVRSKRDVGSYQEKVDVVLGPIQLQSPSKEKRSLDLAVADVEKPASSQEVYPTAAIFGGVFLALVVAVAAFTLGRKTRTARGQPPSTKM

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

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Position	Description	Source
638	N-linked (GlcNAc...) asparagine	UniProt
639	N-linked (GlcNAc...) asparagine	UniProt
651	N-linked (GlcNAc...) asparagine	UniProt
776	N-linked (GlcNAc...) asparagine	UniProt
788	N-linked (GlcNAc...) asparagine	UniProt
838	N-linked (GlcNAc...) asparagine	UniProt
848	N-linked (GlcNAc...) asparagine	UniProt
963	N-linked (GlcNAc...) asparagine	UniProt
1078	N-linked (GlcNAc...) asparagine	UniProt
1079	N-linked (GlcNAc...) asparagine	UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying 1 entry
Pathway Name	Organism
Surfactant metabolism	Rattus norvegicus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

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Summary

External Links

Annotation

International Collaboration

Acknowledgements