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Guanylate cyclase alpha
Summary
- UniProt ID
- Q8IHY1
- Gene Symbol
-
- GCalpha
- PF3D7_1138400
- Gene ID
- 810941
- Organism
- Plasmodium falciparum 3D7
External Links
- Re-Glyco
- Q8IHY1
Annotation
- Keyword
-
- Cell membrane
- Cytoplasmic vesicle
- Glycoprotein
- Lyase
- Magnesium
- Metal-binding
- Reference proteome
- Transmembrane helix
- cGMP biosynthesis
- Gene Ontology (GO)
| GO Term |
|---|
| plasma membrane |
| cytoplasmic vesicle membrane |
| GO Term |
|---|
| intracellular signal transduction |
| cGMP biosynthetic process |
| phospholipid translocation |
| signal transduction |
| GO Term |
|---|
| ATPase-coupled intramembrane lipid transporter activity |
| metal ion binding |
| guanylate cyclase activity |
Sequence
MSDSKKHYNESNVRYKVKYSGKIFGNNMKKLNENNNHDFTTAEAAWMEKKKKLYKDTNNQPLWDFRKIQINPTETDELISFPSNKICSKNYGKYSFIFKGLYEQFLRLPNIWFLLISLLEFIPQYQNLSNYMYYSKHSSFFLLLFFICVSIIKNIYEDSRRSNIDYQINNRLCHMLDGPNSQLKAVRWMELSVGSIIRLIENEQVPADILLLSCNNSEGVVYIETSLLNGETNLNKKYCVNETRNETSIYAISNIRGRIVCEKPNSNMESFNGSLKLDAHPRATSLSINNVIFKGSHIKNTEYIFGVILYTGNDTKIMKNISNNKHKLGYVNKELNSYTIIGLIFTFICVFISVLFKWTEDDKFRNGSHFFLITVKDNICESIVKYTLLYSNIIPISILISVDLISILQSILIENDNHISTFENYETSEPSTIDDMDNELGDFKMDKSHTFFKKYTYFLNNRSKNFTNNRYSSTNTERASDFRKSFFGTFDKLKTIKRYFYSIKSKIKSISQSNTLYNKSSAGGSIIRSDKNKQTTFSKSFIDIFQRTNNNEHSQTLDNNNNNDNNNNNNICKEKYQNVNNSKNVYVSEDSSNNKYKQNDYLQKSQEQNEIHSINNNNYNNKNDNNLQTEFSNHNFRINAYKTNRTTKDDTYNNKHISLNSRSKSNQKGILINSNEINRKKKKNLLQKIFPFFKKKRTNISEDLSKYVFRRSKQLNINHNNSEKYNLNDYDEYGWGLCLNSNMHGDLGNVDFIFTDKTGTLTNNNMTFNMCSIAGKTYGSKCKNKKKIYNNPKSNNDNKLNSYDKNIFKNKFSSEASIKKISFVRDFSNNVSSKNDLTLDDPTELISDEGNNYLRDKYEHTSDKKNDTNKNRDGANNSNNNNNKDVSNNKNKNNNNYNYNSNNDYIKQNGECNIYNNQNNTNNTHNNNIYYDEYNNTNEGNMKNTNVNKDTNSKCNKKDFIINTSDIINNNNNNNNDQKTNNLKYKSSSSWNSKAKKSSYINLNSYNKYQSFQNSSMLSSSLSSTCSSETEDENGSQLMYYSSSNYDNLDINNDMDSTKTYSHYTEQNYYNSVKDDKDINSEHQRYQQKKTNKQTKNIQQNQCDQWEDNRYTQESIKNQYFFDRNYQTFLMKQNFPRPKSFRLNMNSSSVKGRCDFNDTKIYNDLNSQSWRGYYIDEFFKCMTLCHAVTPFIQFDYIRNKHLTYTNSRSSKGISNNMDRYNINPTTTTTNNNNNNNNINNINNINNNNNNNNNNNNNKQFSCDYMKNRNDIIFETSTDYYANQDNAKRKREKTLFDNVSHCGEIQEYRDNKKYRMKRSQTCSNNRKIFSNQRTLYDYRNMNNNLKNKNSYLRNKLKSKIFLDKSYRKRKKSSGTYKGSDICKGIEKKETRRWKRFLHMKGSNNRNIFSRIKDFKSNSIIYNNQDKTNDYKNGYSNNINNNNSNNYTNEKINRSFNKRHSAVSFKQMSKEKLIPINNVLSNRCDVESYPNEELSFSKKKKKNSEIVSFASGKSDIGFEERTDAGIAGKNMELSYNELEKYKYVKHIDSNNKYINNNNNSIHMSHMSSNNNTFESHIYFDAIKYQSSSLDEECLIYSSSFLGYRLVLRNKNTMCIEIDGSFNKWTIIGVNEFTNRRGKMSIVVKPDSMESGSILYVKGSDSSILSLLNLKYSKFLDKKYSRKRRNKNIQKYKQKREEYNELKSKDINIEEFQKSKSLSLKNFKNNTPKVLFGECTLDNNNNNINKNYKYDKNDKHNNNNNNNNNNSNYSYNYLHDSNNLDAMQNQKYSYAYEDKEDYYYTNNGECNKYKERYRRLEKQLRKFSVKGLRSMIFAFRYLSEEETIKYKRMYDDACSSIYNKEQRLEKVAEEFERDLIYLGITGVKNGLQEKVPKTIDILNQSGIRIWMLTGDNVEYSLHVSFLCKFLNKHTKIFHAALENSNAKKLKREGMALYELFQLEKEEKKPYENLCLLVNGRNLQTFLNYTDLQTHFLNMACTCDVVIACRITAKQKAFLVQLIKNRLYPTPNTLAIGDGANDIAMIQEANIGVSIMTSDCIISAGYSDYCIKKFCYLRKLLFIYGSKHLYTISIILYWNFFKNILLILPIFFYQAYASWSCVKIYPELLYTFFSIFWVFIPIIYYMFLQHNLNYDILYNIPLFYALSRRRYNMNCFKFLPWIFEAIFYSMIIYFFAYAALKENSHLNNGEVITINTFGNICFIGCLLISILRLFLEGSLWSPSILITCFGCFLFVFFPSLLFICFAYLSNEYIREVFRQTFLWAPLYVLLILWFSTCIISYIFINFTKSILFPNIYNVVNHWLFEQYQEKHNKNKYIFSLSGKNKFLKLRKLGKKIKFKFKRNYSKKYDTNVIREHPLLHHTFKSEQDQNKCNEQFSKDPFISNSLLKSKNCKFKKDSSYSKSNIHVDEEQTYKGLKVVLSEQVVHAKENLVSFKNEKKNKNNKNTSMNVNDNIIIKNNNINIKNNDNNNDDNDNDNNNNNNNNDNYNNNDHNKKEFKQKHIQNNYENLFNHTQVENNLIKENLSIRNDNNRRDNKNETDYIKQSDEDYEMNPSITSLRKRECINDSKYIDNKSYDNKISNNHEEKDGFKSDDRSLINSNMMDYKNEFTENDTTYSFNDSHMFYDFPSNSKTTKDYKVINSRIDDSIMADMKNCLNPLKNTFLVDLLPPGKRFRINEDHIYFKNNERMENIPEALDVNKKYYHIIQNKAEYYDNDSLSEFSYTSSNSSINNKKKNENTQKEIVKVSHLINRFTLAFKDMQLESGFQIHKKNKFYKTFTPWYRFIFLLLGVFFLYVWKLESSLSQLWNMPSDASTDVFILFLSLLLELVLLAATVTTFFSNIFIENFNKIISAVVILIITYHVVSYSVTHIDGVFQAVLFPLYTFVILRLPFVNAVLCNIIFLGLFIIRFNGDHFLDKKGLAHYIPLFIGVDVFVGFVGYRLEYNQRKNFLLEYSVESSRRKQREILNTMLPPFVVDEMIYSELNEEGIPISLKAEDISTVTIIFCDIYDFQNIVASIEPTRLVEVLDRLFLCFDKCTEQFNCTKIETVFETYLAACGLVKREKDEDELENNKYSNNNKNNNNNYYYNRKKKKKKNNNNNNNNNNNNNNNNNNNNNLNNNNNNNNVNTSDDDGDFFEEDDANNHQIYNQMKGQEDAHDSIDFALSILHVSSHIKYEKSKMMLKKNDSFEDANDDTHNVNDSFNNDKAENDNTNTDNNKPTRIRVKVGIHSGRIIAGVVGSKKPQYALFGDTVNTASRMKTTGKPDYIHISEATYNLVKDDKTLIYEKKETEIKGKGIMTTYLLTSVIGLNYPFLGEHVEKKGHFISELYEDDLSNNLNYDKTQNILGYYSNKINQNNDSNINEGIINNNMNTFNTIDGDTSNYYVNLKDLSLNDLPNEYIKDVNTHYCEIIKLRNLKIGTAVGYQLKQKDFYNMTFLNNGLNNDTATNFNQYIESHKDFDDIKDLRIGMNKLSISDSLYYLNENVIRNEPINEYKNKIKINSVNTNKKSYEDAHLNAGNIIYTNNEYPNGQNIEEDDDLLLTNHYNKTNVNNNNNNNIYDVSKELIEHNEEDYKNILMCSKRCKNCNETYCTPNDCNNNDHVYHVMYHRKLSNIKKNYLKNIRKDANIKKDIEKEELNKIHSNKKSFNFFYLFSYIFKIFPFIGKINKEEKKNKSYKKGEQDKSSKRIIALNSEWIFLKFSDKNLEAKYRAHFYSNKSNINSIEQALIIFLVTFVMQTLISSTVSIVFIDHKRATQTLHINYFAYWSVRSVYTFFGFVLWLLFHYRTRPEVSSLLNIKWMIFFLNLLFISAACVFSIAYLWAISETDQTTSYTIWMTNDTIEFFFYLVILHHNTGMLFQTCILVDLLFITMSLTFIATSVVKTITTDSTVLLIPWYVAFNLISTYCKESIDRRTFYANESAKKTENRATELLNDMLPKHVLEEFQQDKLKLAYTHDRLTFLFADICGFTSWANGVDASEVLTLLQKLFAKFDNDSTKYGLYKLCTIGDAYVAISEPVTEDNKDYDPVDGTERVLEMAYSMIRIIKEIREKLYIPNLNMRIGLHYGSCVGGVIGSGRLRYDLWGIDVLTGNLMESNGIPGKINVSETLKNFLLQQFKNRFIFKPHTTIRVIYKDVKCFIITDKKEVESSNHSKLLQNKNYLLNKKFSTQNYLVKNIFAKKKHSSISSSKNIHSYDEKKKKKNDLFYINVNDRQSNL
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Ion transport by P-type ATPases | Plasmodium falciparum |
| Neutrophil degranulation | Plasmodium falciparum |
