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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Extracellular sulfatase Sulf-2
Summary
- UniProt ID
- Q8IWU5
- Gene Symbol
-
- SULF2
- KIAA1247
- Organism
- Homo sapiens (human)
External Links
- GlycoProtDB
- GPDB0012369
- GlyConnect
- GlyGen
- Q8IWU5
- The Human Metabolome Database
- HMDBP08019
- The O-GlcNAc Database
- Q8IWU5
Annotation
- Keyword
-
- Alternative splicing
- Calcium
- Endoplasmic reticulum
- Golgi apparatus
- Hydrolase
- Metal-binding
- Proteoglycan
- Reference proteome
- Secreted
- Signal
- Gene Ontology (GO)
| GO Term |
|---|
| endoplasmic reticulum |
| Golgi stack |
| cell surface |
| extracellular region |
| extracellular space |
| plasma membrane |
| GO Term |
|---|
| calcium ion binding |
| glycosaminoglycan binding |
| arylsulfatase activity |
| N-acetylglucosamine-6-sulfatase activity |
Sequence
MGPPSLVLCLLSATVFSLLGGSSAFLSHHRLKGRFQRDRRNIRPNIILVLTDDQDVELGSMQVMNKTRRIMEQGGAHFINAFVTTPMCCPSRSSILTGKYVHNHNTYTNNENCSSPSWQAQHESRTFAVYLNSTGYRTAFFGKYLNEYNGSYVPPGWKEWVGLLKNSRFYNYTLCRNGVKEKHGSDYSKDYLTDLITNDSVSFFRTSKKMYPHRPVLMVISHAAPHGPEDSAPQYSRLFPNASQHITPSYNYAPNPDKHWIMRYTGPMKPIHMEFTNMLQRKRLQTLMSVDDSMETIYNMLVETGELDNTYIVYTADHGYHIGQFGLVKGKSMPYEFDIRVPFYVRGPNVEAGCLNPHIVLNIDLAPTILDIAGLDIPADMDGKSILKLLDTERPVNRFHLKKKMRVWRDSFLVERGKLLHKRDNDKVDAQEENFLPKYQRVKDLCQRAEYQTACEQLGQKWQCVEDATGKLKLHKCKGPMRLGGSRALSNLVPKYYGQGSEACTCDSGDYKLSLAGRRKKLFKKKYKASYVRSRSIRSVAIEVDGRVYHVGLGDAAQPRNLTKRHWPGAPEDQDDKDGGDFSGTGGLPDYSAANPIKVTHRCYILENDTVQCDLDLYKSLQAWKDHKLHIDHEIETLQNKIKNLREVRGHLKKKRPEECDCHKISYHTQHKGRLKHRGSSLHPFRKGLQEKDKVWLLREQKRKKKLRKLLKRLQNNDTCSMPGLTCFTHDNQHWQTAPFWTLGPFCACTSANNNTYWCMRTINETHNFLFCEFATGFLEYFDLNTDPYQLMNAVNTLDRDVLNQLHVQLMELRSCKGYKQCNPRTRNMDLGLKDGGSYEQYRQFQRRKWPEMKRPSSKSLGQLWEGWEG
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 65 | N-linked (GlcNAc...) asparagine |
|
||
| 106 |
|
|||
| 112 | N-linked (GlcNAc...) asparagine | |||
| 124 |
|
|||
| 132 | N-linked (GlcNAc...) asparagine | |||
| 149 | N-linked (GlcNAc...) asparagine | |||
| 171 | N-linked (GlcNAc...) asparagine | |||
| 185 |
|
|||
| 198 | N-linked (GlcNAc...) asparagine | |||
| 241 | N-linked (GlcNAc...) asparagine |
G49108TO
G08290VR
G80920RR
G62765YT
G64527OM
G66676MI
G31852PQ
G41247ZX
G48414YA
G70101JE
G52527GH
G83460ZZ
G25079LO
G02815KT
G06110VR
G70087PV
G15664MX
G09197ZW
G68318VE
G47644PP
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050156 | idiopathic pulmonary fibrosis | |
| DOID:0050387 | nonpapillary renal cell carcinoma | |
| DOID:0050865 | tongue squamous cell carcinoma | |
| DOID:0080199 | colorectal carcinoma | |
| DOID:0110425 | dilated cardiomyopathy 1A | |
| DOID:10283 | prostate cancer | |
| DOID:10286 | prostate carcinoma | |
| DOID:10534 | stomach cancer | |
| DOID:10763 | hypertension | |
| DOID:10825 | essential hypertension |
