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Extracellular sulfatase Sulf-1

Summary

UniProt ID

Q8IWU6

Gene Symbol

SULF1
KIAA1077

Organism

Homo sapiens (human)

External Links

GlyConnect

1231

GlyGen

Q8IWU6

The Human Metabolome Database

HMDBP02295

RaftProt

Q8IWU6

Annotation

Keyword

Apoptosis
Calcium
Endoplasmic reticulum
Glycoprotein
Golgi apparatus
Hydrolase
Metal-binding
Reference proteome
Secreted
Signal

Gene Ontology (GO)

Displaying entries **1 - 10** of 22 in total

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GO Term
positive regulation of vascular endothelial growth factor production
glomerular basement membrane development
glial cell-derived neurotrophic factor receptor signaling pathway
regulation of fibroblast growth factor receptor signaling pathway
negative regulation of fibroblast growth factor receptor signaling pathway
embryonic skeletal system development
negative regulation of endothelial cell proliferation
chondrocyte development
vascular endothelial growth factor receptor signaling pathway
innervation

Displaying **all 7** entries
GO Term
endoplasmic reticulum
Golgi apparatus
Golgi stack
cell surface
extracellular space
plasma membrane
membrane raft

Displaying **all 4** entries
GO Term
calcium ion binding
arylsulfatase activity
glycosaminoglycan binding
N-acetylglucosamine-6-sulfatase activity

Annotation information from UniProt.

Sequence

MKYSCCALVLAVLGTELLGSLCSTVRSPRFRGRIQQERKNIRPNIILVLTDDQDVELGSLQVMNKTRKIMEHGGATFINAFVTTPMCCPSRSSMLTGKYVHNHNVYTNNENCSSPSWQAMHEPRTFAVYLNNTGYRTAFFGKYLNEYNGSYIPPGWREWLGLIKNSRFYNYTVCRNGIKEKHGFDYAKDYFTDLITNESINYFKMSKRMYPHRPVMMVISHAAPHGPEDSAPQFSKLYPNASQHITPSYNYAPNMDKHWIMQYTGPMLPIHMEFTNILQRKRLQTLMSVDDSVERLYNMLVETGELENTYIIYTADHGYHIGQFGLVKGKSMPYDFDIRVPFFIRGPSVEPGSIVPQIVLNIDLAPTILDIAGLDTPPDVDGKSVLKLLDPEKPGNRFRTNKKAKIWRDTFLVERGKFLRKKEESSKNIQQSNHLPKYERVKELCQQARYQTACEQPGQKWQCIEDTSGKLRIHKCKGPSDLLTVRQSTRNLYARGFHDKDKECSCRESGYRASRSQRKSQRQFLRNQGTPKYKPRFVHTRQTRSLSVEFEGEIYDINLEEEEELQVLQPRNIAKRHDEGHKGPRDLQASSGGNRGRMLADSSNAVGPPTTVRVTHKCFILPNDSIHCERELYQSARAWKDHKAYIDKEIEALQDKIKNLREVRGHLKRRKPEECSCSKQSYYNKEKGVKKQEKLKSHLHPFKEAAQEVDSKLQLFKENNRRRKKERKEKRRQRKGEECSLPGLTCFTHDNNHWQTAPFWNLGSFCACTSSNNNTYWCLRTVNETHNFLFCEFATGFLEYFDMNTDPYQLTNTVHTVERGILNQLHVQLMELRSCQGYKQCNPRPKNLDVGNKDGGSYDLHRGQLWDGWEG

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 10** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
64	N-linked (GlcNAc...) asparagine			UniProt GlyGen
111	N-linked (GlcNAc...) asparagine		G15664MX G49018RC G72747WU G90659AW G65000LJ G62765YT G64527OM G05724UK G31852PQ G41247ZX	UniProt GlyGen GlyConnect
131	N-linked (GlcNAc...) asparagine		G00912UN G48414YA G06356OH G80920RR G62765YT G72790NZ G95865ZB G02815KT	UniProt GlyGen GlyConnect
148	N-linked (GlcNAc...) asparagine		G01650EU G37399XV G28541PG G39446WN G41247ZX G02815KT	UniProt GlyGen
170	N-linked (GlcNAc...) asparagine		G57776ZS G44753VC G99668VU G86880BF G27947YN G79666IR G40926MX G40574BA G70441OD G83646BJ G27058EU G83460ZZ G59626AS G80920RR G62765YT G10486CT G28541PG G31852PQ G41247ZX G02815KT G06110VR	UniProt GlyGen GlyConnect
197	N-linked (GlcNAc...) asparagine	19159218	G78787DI G83460ZZ G46503DX G48584BU G70101JE G80920RR G62765YT G64527OM G05724UK G31852PQ G49955PK G39188ZX G41247ZX G02815KT G06110VR	UniProt GlyGen GlyConnect
240	N-linked (GlcNAc...) asparagine		G83460ZZ	UniProt GlyGen
623	N-linked (GlcNAc...) asparagine		G72667IM G27058EU G84452RH G80920RR	UniProt GlyGen GlyConnect
773	N-linked (GlcNAc...) asparagine			UniProt GlyGen
783	N-linked (GlcNAc...) asparagine			UniProt GlyGen