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Glycomics MS Repository for glycan annotations from GlycoWorkbench
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Repository for lectin-assisted multimodality data
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Guidelines
MIRAGE
Macrophage colony-stimulating factor 1
Summary
- UniProt ID
- Q8JZQ0
- Gene Symbol
- Csf1 Csfm
- Gene ID
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
- Alternative splicing Cell membrane Cytokine Disulfide bond Growth factor Inflammatory response Innate immunity Proteoglycan Reference proteome Secreted Signal Transmembrane helix
Gene Ontology (GO)
| GO Term | Evidence Code | Reference |
|---|---|---|
| ossification | ||
| neutrophil homeostasis |
|
|
| positive regulation of cell-matrix adhesion | ||
| osteoclast proliferation | ||
| positive regulation of leukocyte migration |
|
|
GO Hierarchy
biological process
multicellular organismal process [inference]
developmental process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
regulation of signaling [inference]
regulation of locomotion [inference]
positive regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of developmental process [inference]
regulation of cell differentiation [inference]
positive regulation of developmental process [inference]
regulation of multicellular organismal development [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of metabolic process [inference]
regulation of cell population proliferation [inference]
regulation of cell differentiation [inference]
positive regulation of cellular process [inference]
regulation of cell motility [inference]
regulation of multicellular organismal process [inference]
| GO Term | Evidence Code | Reference |
|---|---|---|
| extracellular region | ||
| extracellular region | ||
| extracellular region | ||
| obsolete extracellular space |
|
|
| plasma membrane |
GO Hierarchy
| GO Term | Evidence Code | Reference |
|---|---|---|
| cytokine activity | ||
| cytokine activity | ||
| cytokine activity | ||
| macrophage colony-stimulating factor receptor binding | ||
| growth factor activity |
GO Hierarchy
Sequence
MTARGAAGRCPSSTWMGSRLLLVCLLVSRSVAEVSEHCSHMIGNGHLQILQQLIDSQMETACLIEYKFVDQEQLDDPVCYLKKAFVLVQVIIEETMRFKDNTPNANATERLQELSMKLNSCFIKDYKEQNEACVQTYKESPLRLLEKIKNFFNETKNFLEKDWNIFSKNCNDSFAKCSSRDVVTKPDCNCLYPKATPSSDLASASPHQPPAPSMAPLADLAWDDSQRTEGSSLLPSDLPLRIEDPGSAKQRPPRSTCQTLESTEQPNHEDPQPHPSAGAPIPGVEDIIESSMGTNWVLEEASGEASEGFLTQERKFSPSNPVGGSIQAETDRPWARSASSPFPKLTEDQQPTNITDTPLTEVNPMRPTGQTLNNTPEKTDGSSTLREDQQEPRSPHFATLNPQRVGNSATPYAKLLPPKSHSWGIVLPLGELEGKKSTRDRRSPAELKGGPASEGAARPVAQSTRDRRSPAELKGGPASEGAARPVARFNSIPLTDTGSSIQDPQTSAFVFWVLGIILVLLAVGGLLFYSWKRRSHRDPRTLDSSVGRPEGSSLAQDEDRQVELPV
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 106 |
|
|
||
| 153 |
|
|
||
| 171 |
|
|
||
| 302 |
|
|
||
| 353 |
|
|
||
| 355 |
|
|
||
| 357 |
|
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Other interleukin signaling | Rattus norvegicus |
| Post-translational protein phosphorylation | Rattus norvegicus |
| Regulation of IGF Activity by IGFBP | Rattus norvegicus |
| Transcriptional and post-translational regulation of MITF-M expression and activity | Rattus norvegicus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:3070 | high grade glioma | |
| DOID:4780 | anti-basement membrane glomerulonephritis | |
| DOID:13533 | osteopetrosis |
