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MIRAGE
Mitochondrial inner membrane m-AAA protease component AFG3L2
Summary
- UniProt ID
- Q8JZQ2
- Gene Symbol
-
- Afg3l2
- Gene ID
- 69597
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- ATP-binding
- Direct protein sequencing
- Disease variant
- Metal-binding
- Metalloprotease
- Mitochondrion inner membrane
- Reference proteome
- Transit peptide
- Transmembrane helix
- Zinc
- Gene Ontology (GO)
| GO Term |
|---|
| mitochondrion |
| mitochondrial inner membrane |
| m-AAA complex |
| GO Term |
|---|
| membrane protein proteolysis |
| protein autoprocessing |
| protein catabolic process |
| mitochondrial fusion |
| cristae formation |
| mitochondrion organization |
| protein processing |
| mitochondrial protein processing |
| myelination |
| protein maturation |
Sequence
MAHRCLLLWSRGGCRRGLPPLLVPRGCLGPDRRPCLRTLYQYATVQTASSRRSLLRDVIAAYQRFCSRPPKGFEKYFPNGKNGKKASEPKEAVGEKKEPQPSGPQPSGGAGGGGGKRRGKKEDSHWWSRFQKGDFPWDDKDFRMYFLWTALFWGGVMIYFVFKSSGREITWKDFVNNYLSKGVVDRLEVVNKRFVRVTFTPGKTPVDGQYVWFNIGSVDTFERNLETLQQELGIEGENRVPVVYIAESDGSFLLSMLPTVLIIAFLLYTIRRGPAGIGRTGRGMGGLFSVGETTAKVLKDEIDVKFKDVAGCEEAKLEIMEFVNFLKNPKQYQDLGAKIPKGAILTGPPGTGKTLLAKATAGEANVPFITVSGSEFLEMFVGVGPARVRDLFALARKNAPCILFIDEIDAVGRKRGRGNFGGQSEQENTLNQLLVEMDGFNTTTNVVILAGTNRPDILDPALLRPGRFDRQIFIGPPDIKGRASIFKVHLRPLKLDSALEKDKLARKLASLTPGFSGADVANVCNEAALIAARHLSDAINEKHFEQAIERVIGGLEKKTQVLQPEEKKTVAYHEAGHAVAGWYLEHADPLLKVSIIPRGKGLGYAQYLPKEQYLYTKEQLLDRMCMTLGGRVSEEIFFGRITTGAQDDLRKVTQSAYAQIVQFGMNEKVGQISFDLPRQGDMVLEKPYSEATARMIDDEVRILISDAYRRTVALLTEKKADVEKVALLLLEKEVLDKNDMVQLLGPRPFTEKSTYEEFVEGTGSLDEDTSLPEGLQDWNKEREKEEKKEKEKEEPLNEKVVS
Glycosylation Sites
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Mitochondrial protein degradation | Mus musculus |
| Processing of SMDT1 | Mus musculus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050977 | spinocerebellar ataxia type 28 |
