GlyCosmos Portal

Submissions

Lysosomal cobalamin transport escort protein LMBD1

Summary

UniProt ID

Q8K0B2

Gene Symbol

Lmbrd1

Gene ID

68421

Organism

Mus musculus (house mouse)

External Links

GlycoProtDB: GPDB0006726
GlyGen: Q8K0B2
PubChem: Q8K0B2
Re-Glyco: Q8K0B2

Annotation

Keyword

Alternative splicing
Cell membrane
Cobalamin
Cytoplasmic vesicle
Endocytosis
Endoplasmic reticulum
Gastrulation
Glycoprotein
Lysosome
Phosphoprotein
Reference proteome
Transmembrane helix
Transport

Gene Ontology (GO)

Displaying **all 6** entries
GO Term
lysosome
plasma membrane
endoplasmic reticulum membrane
clathrin-coated vesicle
lysosomal membrane
clathrin-coated endocytic vesicle

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying **all 7** entries
GO Term
gastrulation
negative regulation of glucose import
insulin receptor internalization
negative regulation of insulin receptor signaling pathway
negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
clathrin-dependent endocytosis
protein localization to lysosome

Displaying **all 5** entries
GO Term
insulin receptor binding
cobalamin binding
clathrin heavy chain binding
AP-2 adaptor complex binding
protein transporter activity

Annotation information from UniProt.

Sequence

MAAAAAELVIGWCIFGLLLLAILAFCWVYVRKYQSQRESEVVSTVTAIFSLAVALITSALLPVDIFLVSYMKNQNGTFKDWADANVTVQIENTVLYGYYTLYSVILFCVFFWIPFVYFYYEEKDEDDASKCTQIKTALKYTLGFVVICALLLLVGAFVPLHLPNNNNSTEWEKVKLLFEDLGTGQGLAALSFSISSLTLIGMLAAITYTAYGMSALPLNLIKGTRSTAYERLENTEDIEEVEQHIQTIRSKSKDGRPLPARDRRALKQCEERLRTLRKRERHLEFIENSWWTKFCGALRPLKIIWGIFFILVALLFVISLFLSNLDKALHSAGIDSGFIIFGTNLSNPLNMLLPLLQTVFPLDYILITIIIMYFIFTSMAGIRNIGIWFFWIRLYKIRRGRTRPQALLFLCMILLLIVLHTSYMIYSLAPQYVMYGSQNYLIESNITSDAHKGNSTLAVPKRCDADAPKDQCTVTRTYIFLHKFWFFSAAYYFGNWAFLVVFLIGLIVSCCKGKKSVIEGVDEDSDLSDDEPSAYSA

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 7** entries
Position	Description	GlyTouCan ID	Source
75	N-linked (GlcNAc...) asparagine		UniProt GlyGen
85	N-linked (GlcNAc...) asparagine		UniProt GlyGen
166	N-linked (GlcNAc...) asparagine		UniProt GlyGen
167	N-linked (GlcNAc...) asparagine		UniProt GlyGen
344	N-linked (GlcNAc...) asparagine		UniProt GlyGen
445	N-linked (GlcNAc...) asparagine		UniProt GlyGen
454	N-linked (GlcNAc...) asparagine	G92275SC	GlycoProtDB UniProt GlyGen