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Centrosome-associated protein ALMS1
Summary
- UniProt ID
- Q8K4E0
- Gene Symbol
-
- Alms1
- Kiaa0328
- Gene ID
- 236266
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Alternative splicing
- Cilium
- Cytoskeleton
- Phosphoprotein
- Reference proteome
- Repeat
- Gene Ontology (GO)
| GO Term |
|---|
| cytoplasm |
| cilium |
| spindle pole |
| centrosome |
| GO Term |
|---|
| alpha-actinin binding |
Sequence
MEPEDLPWPDELEEEEEEEEEEGEEEEGKKEVENASAAATEEALTSEESGRLEEFEEAGPDLDFNYESQRQESSDEEEDELAKAWLQAHPDRPGSAFSLPPPTPPPPPPPLSPRLRYTPVEHLGKTEVVPLTCRVWQQSSYQDNSRAQFSNSSTMLLETGVRWGSEEDQRTESWHCLPQERDSSQTLAMSQTEIGRVEGTEVPDLPSQEGGLPAQSQCPGKKPKLNVLCSPLLVIQDNFAAPDLPLLTCLIQDQEEVEPDSLFQQSELEFAPLRGIPDKSEDSEWLARPSEVSEALIQATSETSSDLANSCFSISQHPLTEGLQGKAESGVLTRCGDAKYSSLYENLGAQSERIAVLQREVGCSNLGISQASPSSLPSFVPQEPTSEPEYHSSNLRMLRVSPDTLLTTHTHSAGSADQKIGAAVVSSAYSQEIKPGSFHQEELPDRHLNEEIRKVSPALRTAGQKPEMLPVQSSSYSKGMKSIFYQHPVSHGHQGKEPLSVSAVCGSAGNKAFHQLSTLSDSLLTEETWPVSVIPGLGNQKTPLPSEFSLSYSHRGKNLPEDVVKVSTDSGSAHKKADILTASSRTYQHKMKPANIYHQELPDSRVPIGTRKVAFESGPAGQKSGVSHPYGEMPSVFYQQGLPDRHSAKSPTKTFIPGPADQKTDLSPVPPTSSSHAEKPVSPYQLTLPGSHLPEDVFKASSVCKSSDELSGITALTSASYSYKGRPNSSYQQKFPDSHLNEEAQKILGTTGTVDQKTVTPTMSSSFLQKEKPSIFYQQTLPDGGLSEEDLQVSAVPWPADQNIAIPTVTSAAFSQREKPRIFYQQTLSVDRLPGEPLNVLGTSGPPDQNTGAPTVTPSSYFPGEESIIFYQAGFPGNTLSAMSFKVPRISGSTEQTNVTTGSSSSYSVGEKSIIFYHQALPDGRLPQEASPAPADLNTGEPPMYLASCSVGVKPIIFYQQPMSDSQRTKGHKESDVPGPTDQKTGIATVHSTSQSYIGRRTVSYQKEFPDLSEKALKVLGDVGSTEQKTQIPVVSSALLHKEGPSAYQEDLPDLTEEPLQILGVSEEVSSSSYQRKLPDHIEVFLKSVGSGSADRKTGAQIVSSSREKSSGFHQQELPNTGGDAVDAFHPEPVVQEVRKVQTPGAPAGPSSSHFHKEKLSDYQKASPHRDLTESSLKASTVPGLSDQKKKPAVSSGFCLHKEKHEISASALLNCQTAELLTVTQRSCLHREDPAISTVIKPDDQKIPLPTTFHGSSDQKVKPVIFVQKQLRDRDQSEDIPKISTVSEPTVVNTVLPVLLPGSYSHREKSDSFYPQELPDGHLTEVDLKVSSGLGQADQISGLPTGIPGTYSHSEKHQLISEHVQELMDNLNSSESSCLSVDSMPLNSQIDDGVIICKPESLGFANAGCEEMQNIDRGSKTLKEIQTLLMEAENMALKRCNFSVPLVPFRDVNDVSFIRSKKVVCFKESSTTDVCTQRESFVEEVPHIEYVQKDIGTQTNLKYQRGVGNWEFISSATFRSPLQEAEGTARMAYDETFRQYKAARSVMRSEPEGCSTGIGNKMIIPMMTIIKSDSSSDVSDGCCSWDNNLPESLESVSDVFLNFFPYTSPKTSITDSREEEWLSESEDGYGSTDSLAAHVKYLLQCETSLNQAKQILKNAEEEEYRVRTQAWNLKFNLGRDRGYSISELNEDDRRKVEEIKAKLFGHGRATHMSEGLRSPQGIGCLPEAVCSRIIIESHEKGCFRTLTAEQPRPDSCHCAFRSVEPSDLIRGHRSPSSWRGRHINLSRSIEQSNPCFKVGSSFQLQSHPPFQKLLPDDIKISKGVGMPVHAYMDPQPSELVEPTCVPAKEMDFPSSSQILPPEPKKQFTTAITFSSHEHSECISDSSGCKVGVTADSQCSGPSLGVFKPHIPEEQISPRDLKQKTSFQSSLERHGSTPVTILADGSRQRQKLPVDFEHSHQKEKLLQRLGFKVSHSEPNVSTNVSNFKGVQFSGKDTIVSQDKLTSTVEVKEKNVTVTPDLPSCIFLEQPELFEESHTPHTDLQMRKYPSPSCPEIASRIFLEQPKLSEQSKAPHVDREIREDHSFFPKCQDYIVADPSPDFPDQQQCKPPDVVGHTRKQNSLLSEGQDYELEEVQHIPQSYFSNMVNVEAKVSDAISQSAPDHCTAASTPPSNRKALSCVRITLCPKTSSKLDSGTLGERFHSLDPASKTRINSEFNSDLRIISSRSLEPTSKLLTCKPVAQDQESLVFLGPKSPLDLQVAQSSLPDSKTIFQDLKTKPPQNSQIVTSRQTQVNISHLEGYSKPEGTPVSADGSQEQSKVSFTTSFGKLSSDAITQITTESPEKTTFSSEIFIHADDRGQGILDPMAQKPSRFASSSSVQQIPASHGKDAQPVLLPYKPSGSSKMYYVPLLKRVPSYLDSKSDTTVESSHSGSNDAIAPDFPPQMLGTRDDDLSNTVNIKHKEGIYSKRAATKGKNPSQKGDAAAPVQMPITWDENVLDENQEEVISRGVVIKMAGPEEMSSLEKDLAGPSDITVQDRKTENLPDTKSIKQKEGSLEIESECHSAFENTAHSVFRSAKFYFHHPVHLPHEQDFCHESLGRSVFMQHSWKDFFHHHSGHSCLPPPGPSSDKLDKTKMDYTRIKSLSINLNLGEHEKIHTIKNQARDPKGKRQANEQKKDQKVTPELTTECPVSLNELWNRYQERQKQQNPSGACDTKELSLVERLDRLAKLLQNPITHSLRASESAQDDSRGGHRAREWTGRRQQKQKGKQHRKWSKSLERGQSTGDFRKSKVFSPHQGGKSSQFKIEQIKLDKYILRKEPGFNNVSNTSLDSRPSEESVSLTDSPNIFSSTDSPVDSDVLTPTDRDMPLNERSSSISTIDTVRLIQAFGQDRLSLSPRRIKLYSTVTSQRRRYLEQPCKHNRKALNTACPQMTSEHSRRRHIQVANHMTSSDSVSSPGSLLSLDSALSNEETVRMVSKGVQAGNLEIVAGVKKYTQDVGVTFPTPSSSEARLEEDSDVTSSSEEKAKEKKFLSNYLQTKNLRKNKPNPCAGVSWFVPVESGQSGSKKENLPKIYRPVISWFEPVTKTKPWREPLREQNWQAQCMNSRGSLGGPGRDSGQVSLRPFVRATLQESLQLHRPDFISHSGERIKRLKLLVQERKLQSLFQSEREALFHSARPLPRRVLLAVQKNKPIGKKEMIQRTRRIYEQLPEVKKKREEEKRKSEYKSYWLRAQHYKMKVTNHLLGRKVPWD
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 103 |
|
|
||
| 412 |
|
|||
| 672 |
|
|
||
| 750 |
|
|||
| 857 |
|
|
||
| 981 |
|
|
||
| 1030 |
|
|||
| 1784 |
|
|
||
| 2291 |
|
|||
| 3004 |
|
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| AURKA Activation by TPX2 | Mus musculus |
| Anchoring of the basal body to the plasma membrane | Mus musculus |
| Loss of Nlp from mitotic centrosomes | Mus musculus |
| Loss of proteins required for interphase microtubule organization from the centrosome | Mus musculus |
| Recruitment of NuMA to mitotic centrosomes | Mus musculus |
| Recruitment of mitotic centrosome proteins and complexes | Mus musculus |
| Regulation of PLK1 Activity at G2/M Transition | Mus musculus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050473 | Alstrom syndrome | |
| DOID:9970 | obesity |
