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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
D-2-hydroxyglutarate dehydrogenase, mitochondrial
Summary
- UniProt ID
- Q8N465
- Gene Symbol
-
- D2HGDH
- D2HGD
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- Q8N465
- PubChem
- Q8N465
- The Human Metabolome Database
- HMDBP02431
- The O-GlcNAc Database
- Q8N465
- O-GlcNAcAtlas
- Q8N465
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Disease variant
- FAD
- Metal-binding
- Mitochondrion
- Oxidoreductase
- Reference proteome
- Transit peptide
- Zinc
- Gene Ontology (GO)
| GO Term |
|---|
| mitochondrion |
| mitochondrial matrix |
| GO Term |
|---|
| (R)-2-hydroxyglutarate dehydrogenase activity |
| zinc ion binding |
| FAD binding |
Sequence
MLPRRPLAWPAWLLRGAPGAAGSWGRPVGPLARRGCCSAPGTPEVPLTRERYPVRRLPFSTVSKQDLAAFERIVPGGVVTDPEALQAPNVDWLRTLRGCSKVLLRPRTSEEVSHILRHCHERNLAVNPQGGNTGMVGGSVPVFDEIILSTARMNRVLSFHSVSGILVCQAGCVLEELSRYVEERDFIMPLDLGAKGSCHIGGNVATNAGGLRFLRYGSLHGTVLGLEVVLADGTVLDCLTSLRKDNTGYDLKQLFIGSEGTLGIITTVSILCPPKPRAVNVAFLGCPGFAEVLQTFSTCKGMLGEILSAFEFMDAVCMQLVGRHLHLASPVQESPFYVLIETSGSNAGHDAEKLGHFLEHALGSGLVTDGTMATDQRKVKMLWALRERITEALSRDGYVYKYDLSLPVERLYDIVTDLRARLGPHAKHVVGYGHLGDGNLHLNVTAEAFSPSLLAALEPHVYEWTAGQQGSVSAEHGVGFRKRDVLGYSKPPGALQLMQQLKALLDPKGILNPYKTLPSQA
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 60 |
|
|||
| 61 |
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Interconversion of 2-oxoglutarate and 2-hydroxyglutarate | Homo sapiens |
